Tropical Journal of Natural Product Research

Abstract

environmental differences affect the antibacterial activity of active plant compounds. Therefore, choosing agroclimatic conditions that provide optimal compound activity is essential. Currently, the search for sources of bioactive compounds has shifted to endophytic microbes as the search for natural compounds from plants has increased. 16 Endophytes are an alternative for producing bioactive compounds of plant origin derived from slow-growing and endangered plants. They are a solution when secondary metabolites are not commercially available and are difficult to synthesize because they are heavy molecules or molecules with complex structures. 17,18 Endophytic fungi inhabit plants without causing any symptoms. Several studies have reported the beneficial role of endophytic symbiosis, which positively influences the physiological activities of host plants, such as growth hormone production, increasing host