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NATURAL LANGUAGE PROCESSING USING DEEP LEARNING: A COMPREHENSIVE REVIEW OF MODELS, TECHNIQUES, AND FUTURE DIRECTIONS

Aug 2026 · Genetics and Molecular Research · 0 citations · 15 references

Abstract

Natural language processing (NLP) has emerged as a key focus of AI research for the analysis, interpretation, extraction, summarisation, and generation of human language. The vast amount of unstructured textual data in scientific research, electronic health records, clinical notes, radiology reports, public health documents, and digital health platforms has driven the demand for sophisticated computational tools and techniques capable of extracting structured and actionable knowledge from language. NLP has been greatly advanced by deep learning, which allows for automatic representation learning, understanding context, modeling sequences, and generating large amounts of language by means of structures like CNN, RNN, LSTM, GRU, attention mechanisms, transformers, and large language models. This review aims to present a detailed overview of deep learning-based NLP models, methods, applications, challenges, and future directions, focusing on biomedical informatics, clinical text mining, digital health and biomathematical relevance. It has numerous applications such as biomedical literature mining, named entity recognition, relation extraction, clinical decision support, pharmacovigilance, radiology report generation, public health surveillance, and construction of knowledge graph. The specific focus lies in the application of NLP to identify biological entities, clinical variables and quantitative evidence that can be used to support biomathematical modeling. There are several current challenges such as domain shift, privacy, hallucination, bias, interpretability, and reproducibility. The success of future progress relies on reliable, comprehensible, domain specific and clinically verified NLP systems.

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