Aug 2026· Therapeutic delivery· pp.
1-40
· 0 citations
Medicine
TL;DR
This review highlights recent advances in exosome biology, cargo-sorting mechanisms, and engineering strategies designed to enhance therapeutic delivery and targeting within the central nervous system and discusses how exosomes compare with conventional delivery platforms and critically examine the major barriers limiting their clinical translation.
A pathology-driven and engineering-guided perspective for understanding the rational design and future development of exosome-based therapeutics for CNS disorders is provided.
This review explores the biological properties of exosomes, recent engineering advances to improve their therapeutic potential, and new methods to leverage their versatility for selective delivery of remedial agents to the brain and provides a roadmap for harnessing these methods effectively as medical interventions fo...
M. Abubakar, Ritu Dahiya, Lokesh Nama et al.· CNS and Neurological Disorde...· 0 citations
This review provides an in-depth examination of exosome biogenesis, current isolation methodologies, and surface engineering strategies, while critically evaluating the strengths and limitations of each approach.
Sourin Bhukta, N. Palei, Vishakha Jaiswal et al.· CNS and Neurological Disorde...· 0 citations
This review highlights the biological characteristics, biogenesis, sources, isolation, purification, and characterization techniques of exosomes, and summarizes the applications of exosome-based drug delivery in cancer, neurological disorders, cardiovascular diseases,inflammatory conditions, infectious diseases, regene...
Snehal Dasharath Pawar, Anis Fathima M S, Nikitha A C et al.· The Bioscan· 0 citations
The growing applicability of EVs as next-generation platforms for precision medicine, targeted drug delivery, and regenerative therapies is summarized while identifying the major obstacles that must be addressed to facilitate their successful clinical translation.
Shery Jacob, Namitha Raichel Varkey, S. Boddu et al.· Pharmaceutics· 0 citations
This review critically examines the current state of exosome-based therapeutics, focusing on isolation methods, engineering strategies, and clinical translation through early 2024, holding promise in oncology, cardiovascular disease, neurological disorders, and regenerative medicine.
Yuvaraj Nitin Sharma· Global Journal of Research i...· 0 citations
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