Aug 2026· Journal of Dairy Science· 0 citations· 69 references
Medicine
TL;DR
Overall, this work provides researchers and industry stakeholders with a technological framework to accelerate the integration of synthetic biology into next-generation dairy food development.
Abstract
Synthetic biology has played a foundational role in the dairy industry for decades, with continued advancements improving the efficiency, precision, and scalability of producing recombinant dairy foods and additives. As global demand shifts, the industry faces growing pressure to deliver products that are nutritionally optimized, sustainable, cost-effective, and broadly accessible. At the same time, numerous value-added dairy components, such as bioactive proteins and functional metabolites, remain underleveraged despite their biological and commercial potential. Synthetic biology offers a platform to industrialize these products. This review examines approaches in protein engineering, genetic modification, and heterologous expression of high-value dairy products in non-native organisms. Overall, this work provides researchers and industry stakeholders with a technological framework to accelerate the integration of synthetic biology into next-generation dairy food development.
This review analyzes precision fermentation as a strategic tool for the future of the global food system, examining the interplay among technological advances, regulatory frameworks, factors influencing consumer acceptance, and associated ethical implications. Recently, synthetic biology has emerged as a prominent fiel...
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This work explores the development of animal-free proteins produced in laboratory settings using innovative technologies such as precision fermentation, submerged fermentation, plant cell culture, and molecular engineering, which enable the production of high-quality proteins without relying on animal farming or large-...
Dairy proteins are among the most nutritionally and functionally valuable proteins used in food, clinical nutrition, and infant nutrition, yet their supply remains structurally linked to livestock production and dairy processing streams. Precision fermentation offers, based on proven technology, a route to produce indi...
Mathilde Pinon, Per Falholt, T. Schmidt et al.· Trends in Biotechnology· 0 citations
The escalating global population and the environmentally inefficient nature of livestock-based protein production are intensifying demand for sustainable and scalable protein alternatives. Microbial biosynthesis, employing engineered cell factories, represents a pivotal strategy for producing functional proteins with a...
Zewei Lu, Zhuoer Chen, Dianqi Yang et al.· Comprehensive Reviews in Foo...· 0 citations
With global population growth, escalating ecological pressures, and evolving consumer demands for health-conscious products, traditional animal and plant protein supply models face numerous challenges-including resource scarcity, high carbon emissions, and limited nutritional diversity. The development and application...
Meng-Ling Ni, Yi Zhou· Global Agronomy Research Jou...· 0 citations
Recent advances and future potential in engineering methylotrophic yeasts for food protein production, with particular focus on Komagataella phaffii are reviewed, addressing the dual goals of improving both yield and quality.
Bing-Yin Peng, Masahiro Tominaga, Jun Ishii et al.· Metabolic Engineering· 0 citations
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