Jul 2026· International Journal For Multidisciplinary Research· Vol 8· 0 citations· 9 references
TL;DR
The cellular and structural processes that allow the brain to reorganise its neural pathways in response to internal and external stimuli are examined, highlighting the critical role of neuroplasticity in lifelong learning, memory formation, and functional recovery following traumatic brain injuries or strokes.
Abstract
Broadly speaking, neuroplasticity can be defined as the nervous system’s ability to adapt as a response to intrinsic or extrinsic stimuli by reorganising its structure, functions, or connections. Once a highly debated concept in neuroscience, neuroplasticity is now recognised as a fundamental mechanism by which the human brain adapts, learns, and recovers throughout our lives. This paper examines the cellular and structural processes that allow the brain to reorganise its neural pathways in response to internal and external stimuli. It also highlights the critical role of neuroplasticity in lifelong learning, memory formation, and functional recovery following traumatic brain injuries or strokes. Furthermore, the clinical implications of self-directed neuroplasticity are explored, demonstrating how intentional behavioural changes can aid in the treatment of mental health disorders like depression and anxiety. Ultimately, understanding neuroplasticity shifts the standard of the human brain from a static organ to a dynamic, mouldable system, emphasising that cognitive potential is not fixed at birth but continuously shaped by experience.
This manuscript distil theoretical approaches to emergence into a practical framework for assessing system behaviour focussed on “novelty” as a necessary condition for emergence and identifies a range of ways in which novelty can arise.
K. C. A. Wedgwood, Patrick McGivern, Alexander R. Harris· Frontiers in Neuroscience· 0 citations
Neuroplasticity, the capacity of the nervous system to alter its structure, function and connectivity in response to intrinsic and extrinsic stimuli, has moved from a developmental curiosity to a central organising principle of contemporary neuroscience and a plausible therapeutic target across neurology, psychiatry, p...
Vivek Patel, Madhuri Dubey, Radhika Patel et al.· Genetics and Molecular Resea...· 0 citations
The pathophysiology of depression involves multiple biological processes, including circuit dysfunction and impaired neuroplasticity, yet an integrative view linking these processes remains elusive. Here, we identify a convergent circuit for antidepressant response and plasticity modulation. We demonstrate that chemoge...
M. Veleanu, Louise Schuberth, Antje Kilias et al.· Nature Communications· 0 citations
It is proposed that positioning CA alongside RN as a core design principle can sharpen target selection, guide stratified treatments and translate known compensatory signatures into testable neuromodulation protocols, providing a framework for improving cognition in psychiatric and aging populations.
S. Grover, Wen Wen, Robert M. G. Reinhart· Nature Neuroscience· 1 citation
The impacts of endocannabinoids, the neurotrophin Brain-derived Neurotrophic Factor, and cell adhesion systems in both medial and lateral compartments of the OFC are summarized to highlight other neuromodulatory factors that have received less attention but are also potent regulators of OFC-dependent decision making.
Sophie T. Yount, T. T. Towner, S. Gourley· Neurobiology of Disease· 0 citations
First-line dictionary definitions of “plasticity” describe it as the ability (of a thing) to be shaped or molded; we call this “plasticity proper” (PP). In neuroscience, however, “neural plasticity” or “neuroplasticity” is defined as an induced change in brain function or structure. These two plasticities are not the...
R. Carhart-Harris, R. Zeifman, L. Pasquini et al.· Frontiers in Neuroscience· 0 citations
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