AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
TL;DR
The study suggests a shared inflammatory and immune-mediated transcriptomic program linking AMI and PD, and identifies FCN1 and LYN as candidate shared immune markers.
Atherosclerosis (AS), a chronic inflammatory disease driven by lipid accumulation and immune dysregulation, predisposes to acute cardiovascular events via plaque rupture and thrombosis. The molecular mechanisms linking immune microenvironment imbalance to plaque instability remain incompletely defined. Utilizing the GS...
Acute myocardial infarction (AMI) is a major global health burden. Current diagnostic reliance on high-sensitivity cardiac troponin (hs-cTn) is limited by its lack of disease specificity and inability to reveal upstream molecular and immune mechanisms. This study aimed to identify robust core genes and their functional...
Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality worldwide, highlighting the need for novel complementary biomarkers. By integrating bulk and single-cell transcriptomic data with machine learning approaches, calmodulin-related genes associated with AMI and explored their immune-metabolic...
Objective The interplay between periodontitis (PD) and rheumatoid arthritis (RA) is well recognized, with aging being a central risk factor for both. However, the shared aging-related molecular mechanisms remain unclear. We aimed to identify common aging-related hub genes linking PD and RA and elucidate their underlyin...
Background Antiphospholipid syndrome (APS) is an acquired autoimmune disorder characterized by recurrent vascular events in large, medium, or small vessels. These events contribute to cardiovascular disease primarily through thrombosis and atherosclerosis (AS). Carotid atherosclerosis (CAS) represents a particularly hi...
Objective To characterize shared immune-associated programs between sepsis and systemic lupus erythematosus (SLE), define the cellular context of prioritized candidate genes, and functionally evaluate SIGLEC1 in macrophage inflammatory responses. Methods Public transcriptomic datasets were analyzed to identify common d...
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