Aug 2026· Engineering, Technology & Applied Science Research· 0 citations· 31 references
TL;DR
The proposed web-based system is a valuable tool for supporting early ASD detection in under-resourced environments, as its combination of validated screening tools and machine learning predictions enhances diagnostic workflows, enabling earlier intervention and better clinical decision-making.
Abstract
Early diagnosis of ASD is crucial for timely intervention, especially in low-resource environments where access to specialized evaluation is limited. This study aimed to develop and validate a web-based application, supported by machine learning algorithms, to assist in the early detection of ASD using behavioral screening questionnaires. A responsive web application was designed using Django (backend) and React (frontend), deployed on Amazon Web Services. The system collects responses to the Q-CHAT-10 questionnaire from caregivers and uses multiple supervised learning models to predict ASD risk. The data used for model training and evaluation were obtained from a public ASD screening dataset. Data preprocessing, SMOTE for class balancing, and hyperparameter tuning through GridSearchCV were applied. Clinical validation was performed through pilot testing at a hospital in Lima, Peru. Among the tested models, the Support Vector Machine, Random Forest, and XGBoost classifiers achieved the highest performance, with F1-scores exceeding 0.90. The system showed a 80% reduction in processing time for the clinical evaluation process compared to the traditional workflow. Clinicians reported improved efficiency and usability, and the application demonstrated strong potential for scalable deployment in similar clinical settings. The proposed web-based system is a valuable tool for supporting early ASD detection in under-resourced environments, as its combination of validated screening tools and machine learning predictions enhances diagnostic workflows, enabling earlier intervention and better clinical decision-making.
XGBoost is the most suitable algorithm for clinical decision support in early ASD screening within the scope of this dataset, indicating strong generalizability.
The early identification of autism spectrum disorder (ASD) is essential for enhancing the developmental process, but the existing conventional approaches, including machine learning, are usually marred by the problem of subjectivity, cultural biases, lack of scalability, and the inability to process tabular questionnai...
The proposed ensemble-based machine learning classifier methodology presented in this study seeks to revolutionize the diagnosis of ASD by harnessing the collective power of various machine learning algorithms to enhance diagnostic precision, mitigate the subjectivity associated with traditional diagnostic methods, and...
Shabeena Lylath, Laxmi B. Rananavare· IAES International Journal o...· 0 citations
The need to develop large, well‐balanced datasets, the application of explainable AI techniques, standardization and regulatory guidelines for facilitating the clinical translation of ASD detection systems are suggested.
Anupama N, Chandrashekar M. Patil· International Journal of Dev...· 0 citations
This research contributes to the development of a machine learning-based decision support system integrated with clinical knowledge through the Q-CHAT-10 cut-off post-processing rule.
Adam Galuh Bhakti, Brestina Gultom· METHODIKA: Jurnal Teknik Inf...· 0 citations
The results suggest that the use of AI to detect ASD is not yet ready for clinical use, and transparent reporting of validation, independent external cohorts, diverse datasets, and prospective testing of positive predictive value in realistic population prevalence should be the focus of future research.
Shivani Pant, A. Gehlot, Neha Singh et al.· International Journal for Gl...· 0 citations
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