Aug 2026· Clinical Research in Cardiology· 0 citations· 43 references
Medicine
TL;DR
A dose-dependent effect on subclinical cardiac function is suggested in childhood cancer survivors treated with anthracyclines, and incorporating CMR-FT strain assessment into the cardiac monitoring of CCS may help identify subclinical CTRCD in this population.
It is suggested that RV strain assessment provides information complementary to conventional LV–based cardiotoxicity criteria and may occur in the absence of concurrent changes in conventional LV cardiotoxicity parameters as currently defined.
Z. Tlegenova, A. Amanova, S. Balmagambetova et al.· European Heart Journal, Supp...· 0 citations
In this cohort of women treated with anthracyclines and anti-HER2 therapy, RV-FWLS identified patients who developed CTRCD, supporting RV strain as a useful tool for early risk stratification and refinement of cardio-oncology surveillance strategies.
B. Andrade, N. Cotrim, C. Coelho et al.· European Heart Journal, Supp...· 0 citations
LA phasic dysfunction was most evident in young adult CCSs despite preserved conventional diastolic indices, suggesting that age-stratified LA strain assessment may help identify survivorship stages at which atrial dysfunction becomes detectable.
Hiroyuki Sato, Ken Takahashi, Yumiko Hosono et al.· International Heart Journal· 0 citations
LV GLS appears to be a sensitive and clinically useful echocardiographic marker for the early detection of anthracycline-induced cardiotoxicity in adult breast cancer patients and may improve identification of subclinical cardiac dysfunction before a measurable decline in left ventricular ejection fraction occurs.
T. Mainka, Emil Sergejuk, W. Kotlarski et al.· International Journal of Inn...· 0 citations
Anthracyclines remain a cornerstone of breast cancer therapy but carry a significant risk of cancer therapy-related cardiac dysfunction (CTRCD). This study evaluates the incidence of CTRCD in an Indonesian setting using the latest 2022 ESC Cardio-Oncology guidelines, focusing on subclinical markers such as high-s...
In this cohort of HER2-positive breast cancer patients treated with anthracycline and trastuzumab LV CTRCD was the commonest type of CTRCD, however RV/BV CTRCD occurred in 7% of patients with distinct temporal patterns.
T. Gonçalves, S. Cai, J. Weiss et al.· European Heart Journal, Supp...· 0 citations
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