The Application of Anti-inflammatory Diet Patterns in Weight Control of Obese Population: Mechanism and Clinical Manifestations

Abstract

Obesity is now a serious public health problem worldwide, which is closely related to chronic low-degree inflammation and metabolic disorders. Over recent decades, people have been paying increasing attention to the anti-inflammatory diet in obesity management. This review summarizes the potential mechanism and clinical effect of anti-inflammatory diet in weight control of obese people. The relevant research on the anti-inflammatory diet pattern, mainly the Mediterranean diet (Med) and Dietary Approaches to Stop Hypertension (DASH) were analyzed. Current studies show that anti-inflammatory dietary patterns are very useful to improve obesity by reducing the level of inflammatory factors, enhancing insulin sensitivity, improving adipose tissue function, regulating intestinal microbiota and promoting energy metabolism. In addition, some clinical studies suggest that long-term adherence to an anti-inflammatory diet is linked to lower body mass index (BMI), and it can reduce visceral adipose tissue (VAT) accumulation and improve metabolic health. These findings show that an anti-inflammatory diet may help control weight and prevent obesity-related complications. Overall, an anti-inflammatory diet provides a practical and sustainable way to prevent and manage obesity. However, the optimal components of anti-inflammatory diets and their effects in different populations remain unclear. Research needs to be further carefully designed, with larger populations and longer-term follow-up periods to provide stronger evidence for its clinical application.