Influence of xenograft with and without 10% collagen for ridge preservation in periodontally compromised molars: A randomized clinical trial.

STATEMENT OF PROBLEM Evidence for alveolar ridge preservation (ARP) using deproteinized bovine bone mineral with or without collagen (DBBM-C versus DBBM) in periodontally compromised molars is limited.

Purpose

The purpose of this randomized clinical trial was to assess clinical outcomes following ARP using DBBM-C and DBBM in periodontally compromised molars. MATERIAL AND

Methods

Forty-six participants were included and divided into DBBM and DBBM-C groups using simple randomization to receive an ARP procedure. Hard tissue changes were assessed by cone beam computed tomography (CBCT) at baseline and 6 months after surgery. Soft tissue contour changes were assessed by intraoral scans immediately and at 2 weeks and 1, 3, and 6 months postoperatively. Treatment costs and implant placement feasibility were recorded after implant therapy. Group comparisons at baseline and outcome used t tests and Mann-Whitney U, chi-square, or Fisher exact tests (by data distribution), with repeated-measures ANOVA for soft tissue contour changes.

Results

The DBBM and DBBM-C exhibited comparable augmentation in central bone height and ridge width (P=.201 and P=.166). The mean collapse of buccal soft tissue contour in the DBBM-C group was 0.99 mm (vertical: P=.040), 1.12 mm (horizontal: P=.013) and less than that in the DBBM group. Neither implant placement feasibility (P=.607) nor total treatment costs (P=.158) revealed significant differences between the groups.

Conclusions

Within the limitations of this study, DBBM and DBBM-C showed comparable outcomes regarding ridge dimension changes, implant placement feasibility, and overall treatment costs. DBBM-C demonstrated less soft tissue contour resorption.