Open access
Routine Blood Indicators Combined With Sleep Questionnaires for the Identification of Cognitive Impairment in Parkinson's Disease: A Cross‐Sectional Study With a Leakage‐Free Nested Modeling Framework
Zi-Yi Wang
TszLeong Lam
Shuo Zhang
Chuan-Jin Song
Xiao-Xue Pei
Jun-Hong Zhong
Bin Li
Gui-Lin Liu
Ying-Xue Cui
Shaosong Wang
Medicine
Abstract
Cognitive impairment (CI) is a prevalent non‐motor complication of Parkinson's disease (PD), yet accessible and reliable screening aids remain limited. This cross‐sectional study aimed to quantify the strength of association and the cross‐sectional classification value of routine blood indicators combined with standardized sleep questionnaires for prevalent CI in PD, using a strictly leakage‐free model‐development pipeline.