Jun 2026· arXiv.org· Vol abs/2606.18613· 0 citations· 56 references
Computer Science
TL;DR
PhysAssistBench is introduced, a benchmark for interactive doctor-patient-EHR assistance that uses a scalable pipeline to construct agentic patients: interactive, record-grounded agents that turn static EHR records into multi-turn clinical scenarios while preserving clinical factuality.
Abstract
The most plausible near-term role of medical LLMs is to assist rather than replace physicians, yet current evaluations often test isolated capabilities: clinical knowledge, EHR system interaction, or patient communication. Physician assistance instead requires coordinating these capabilities within the same interaction, where physicians issue underspecified requests, patients describe symptoms ambiguously, and EHR systems demand precise tool use. We introduce PhysAssistBench, a benchmark for interactive doctor-patient-EHR assistance. Built from real MIMIC-IV cases, PhysAssistBench uses a scalable pipeline to construct agentic patients: interactive, record-grounded agents that turn static EHR records into multi-turn clinical scenarios while preserving clinical factuality. PhysAssistBench provides a curated bilingual evaluation set of 1,296 manually reviewed and physician-validated turns. Experiments with leading LLMs show that current models remain unreliable in this setting, which exposes a key bottleneck for clinical LLMs: reliable assistance requires coordination across knowledge, communication, and systems, not isolated gains in any of them.
Medical benchmarks are dominated by single-turn, multiple-choice clinical cases that poorly reflect real consultations. Practically, clinicians elicit evidence interactively and patient communication varies widely. We introduce MedRoundsQA, a multi-turn diagnostic benchmark derived from 1,387 board-exam cases across 17...
Youssef Mohamed, Ahmed Heakl, Qin-Rong Cui et al.· 0 citations
In hospital workflows, electronic health records (EHRs) are often noisy, and may not contain the evidence needed to confirm events or measurements referenced in a clinical query. Even when database retrieval succeeds, clinical agents can overlook such discrepancies and return plausible but unsupported answers. We intro...
Yi-Tong Qiao, Yan-Cheng Jin, Lei Liu et al.· 0 citations
This review explores the transformative impact of Large Language Models on medical question-answering robots and addresses critical challenges faced by LLM-driven systems, such as limited interpretability, restricted applicability across medical domains, and serious concerns about patient privacy.
A comprehensive framework for transforming LLMs into trustworthy medical specialists is presented, and the evolution toward agentic AI systems that orchestrate them for autonomous, collaborative clinical decision-making is explored.
Kiduk Kim, Jeong Min Song, Dong Yeong Kim et al.· Cell Reports Medicine· 0 citations
Clinical LLM assistants must reason over multi-visit patient trajectories, yet whether the compact history representations used to scale them---retrieval, structured timelines, LLM summaries, agentic memory---preserve the longitudinal signal clinical reasoning needs has not been measured. We introduce ClinTraceBench: 3...
ObGynLongBench is introduced, a rule-grounded long-context EHR benchmark for obstetric and gynecologic decision-making, comprising 1,500 clinical decision-point cases from 976 real pregnancy EHR histories and traceable rules.
Jun Xiang, Zhi-Jie Bao, Rong Hu et al.· 1 citation