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Review Open access

Efficacy of Neuromuscular Electrical Stimulation in Mitigating Muscle Mass Loss: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Sep 2026 · Muscle and Nerve · Vol 74, pp. 1387 - 1397 · 0 citations · 57 references
Medicine

TL;DR

A systematic review and meta‐analysis aimed to quantify the stand‐alone effect of neuromuscular electrical stimulation on muscle mass in adults with sarcopenia or secondary muscle loss and explore whether population, stimulation parameters, and assessment methods modified treatment effects.

Abstract

Evidence for the stand‐alone effect of neuromuscular electrical stimulation (NMES) on muscle mass in adults with sarcopenia or secondary muscle loss remains fragmented. This systematic review and meta‐analysis aimed to quantify this effect and explore whether population, stimulation parameters, and assessment methods modified treatment effects.

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