Journal of Population Therapeutics & Clinical Pharmacology

Abstract

Vitamin D is a fat-soluble vitamin that is indispensable for the proper functioning of the human body due to its ability to influence the processes of calcium-phosphate metabolism, immune response, and cell differentiation. It has been suggested that it harms female fertility and IVF success rate with ovarian function, hormonal changes, and receptivity of endometrium. Therefore, Vitamin D deficiency and its relationship with infertility, especially among women seeking fertility treatment through IVF, has remained inconclusive. Purpose of the meta-analysis: Here, the writer intends to estimate the association between Vitamin D deficiency and female infertility, particularly with IVF implantation rates, pregnancy, live birth rates, and miscarriage rates. A literature search was performed using databases including PubMed, Scopus, and Web of Science with regards to “Vitamin D deficiency,” “female infertility,” “IVF outcomes,” and “fertility treatment.” In this review, a quantitative analysis was done for the eligible populations from specified study types of research