Quantitative and comparative assessment of Tc-99 m MIBI imaging in parathyroid adenomas: associations with biochemical, morphological, and histopathological.
Oct 2026· Annals of Nuclear Medicine· 0 citations· 16 references
Medicine
TL;DR
Tc-99 m MIBI SPECT/CT-derived SUVmax was significantly associated with adenoma volume in patients with primary hyperparathyroidism and its potential relationships with histopathological characteristics require further validation in larger prospective studies.
BACKGROUND
Accurate preoperative localization of hyperfunctioning parathyroid tissue is paramount for the success of minimally invasive parathyroidectomy in primary hyperparathyroidism (PHPT). Conventional imaging with 99mTc-sestamibi (MIBI) scintigraphy and cervical ultrasonography (US) has significant limitations in...
Mohammed Al Rowaily, Sundus H. Albakhiti, Badria Alasmari et al.· Applied Radiation and Isotop...· 0 citations
Hybrid SPECT/CT compare with planar scintigraphy showed a high diagnostic precision in localization of the parathyroid adenoma and support the importance of investment in hybrid SPECT/CT where PET/CT was not available.
Ismet R. Bajrami· International Journal of Med...· 0 citations
Abstract Background Primary hyperparathyroidism (PHPT) is a common endocrine disorder that often requires surgical intervention. Preoperative localization of parathyroid lesions is critical for successful surgery. This study compares the diagnostic value of 99mTc‐MIBI/99mTcO4 − dual‐isotope SPECT/CT fusion imaging and...
Yan-Mei Li, Dan-Na Hou, Zhehao Lyu et al.· Journal of Applied Clinical...· 0 citations
Findings support a stepwise approach to preoperative imaging for focused parathyroidectomy with combining ultrasonography, 99mTc-sestamibi scintigraphy, and four-dimensional computed tomography for localization accuracy.
Erdogan Ozgur, Özden Savaş, A. F. Bayrak et al.· Turkish Archives of Otorhino...· 0 citations
A DLCT-based multiparametric radiomics model, integrated with clinical-radiological features, enables accurate preoperative, noninvasive differentiation between benign and malignant SPNs, including subcentimeter nodules.
Yan-Yan Wang, Ye Yu, Yi-Cheng Fu et al.· Insights into Imaging· 0 citations
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