AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
TL;DR
The interactions between MZ B cells, CD4 T cells, and other immune components in the spleen are investigated, providing a deeper understanding of the molecular mechanisms underlying FVIII inhibitor development.
Humoral immune responses rely on germinal center (GC) reactions to generate long-lasting antibody responses with affinity maturation. CD137 (4-1BB) agonists are known to exert inhibitory effects on B-cell responses; however, the underlying mechanisms remain unclear. Here, we show that agonistic anti-CD137 monoclonal an...
ABSTRACT Introduction B cell plays a pivoting role in the pathogenesis of systemic lupus erythematosus (SLE). In addition to the production of autoantibodies, B cells present antigens to activate the T cells and release proinflammatory cytokines that are relevant for disease activity. B cell modulation remains the spot...
Background and Aims. Haemophilia A (HA) is an X-linked bleeding disorder caused by factor VIII (FVIII) deficiency, treated with FVIII infusions or, more recently, emicizumab subcutaneously. Although emicizumab is safe and effective, FVIII is still required for severe bleeding, trauma, or surgery, and few studies have c...
The structure, function, and receptor interactions of CD155 (PVR), with a particular focus on its immunoregulatory role in the ovarian tumor microenvironment are reviewed.
BACKGROUND Teclistamab is a bispecific monoclonal antibody that targets B cell maturation antigen (BCMA) on plasma cells and other B lineage cells and CD3 on T cells, thereby redirecting cytotoxic T cells to eliminate BCMA-expressing antibody-producing cells. Autoantibody-mediated coagulation disorders are often driven...
We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.