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An inflammation-associated five-gene expression signature stratifies survival and immune states in lung adenocarcinoma: an integrative public-cohort analysis

Xing-Chen Zhou Zhen Le Pengxia Song Qian Xu Ming Chen Xiao-Bo Liu Meng-Nan Cao Si-Jie Zhan Yu-Bin Liu Lin Zhang
Aug 2026 · bioRxiv · 0 citations · 52 references
Biology

TL;DR

Public LUAD transcriptomes identified two inflammation-associated subtypes and a five-gene score comprising CHRDL1, FDCSP, CXCL13, CYP4B1, and S100P that separated survival groups and marked distinct proliferative and immune expression programs.

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