Aug 2026· Surgery today (Print)· 0 citations· 8 references
Medicine
TL;DR
Salvage resection for isolated LLNR provides an acceptable OS, but re-recurrence remains frequent, and careful patient selection using PET-CT and multidisciplinary discussions are essential, particularly for patients who require extensive surgery.
Background/Aim Locally recurrent rectal cancer (LRRC) remains challenging, and optimal treatment strategies vary by recurrence location. We retrospectively evaluated treatment patterns and outcomes of LRRC without distant metastasis, focusing on the Memorial Sloan Kettering Cancer Center (MSKCC) pelvic compartment clas...
S. Nambara, K. Ando, Tetsuro Kawazoe et al.· Cancer Diagnosis & Prognosis· 0 citations
Purpose Total mesorectal excision (TME) is the standard treatment for early rectal cancer, but radiation therapy (RT) with or without chemotherapy may be considered as an alternative organ-preserving option. This study evaluated the oncologic outcomes, patterns of failure, salvage treatment efficacy, and TME–free survi...
Seo Jin Lee, H. K. Byun, Jee-Suk Chang et al.· Radiation Oncology Journal· 0 citations
Despite advances in diagnosis and treatment, locally recurrent rectal cancer (LRRC) remains a complex condition associated with a poor prognosis. This study aimed to evaluate long-term trends in the management of and oncological outcomes for patients with LRRC treated in a Dutch tertiary referral center. All consecutiv...
F. E. C. Vande Kerckhove, D. Creemers, E. Banken et al.· Annals of Surgical Oncology· 1 citation
Achieving salvage R0 resection provides a significant survival benefit comparable to repeat hepatectomy outcomes, and aggressive local intervention aimed at R0 resection should be considered a key therapeutic strategy.
S. Hashimoto, T. Tominaga, T. Shiraishi et al.· Annals of Surgical Oncology· 1 citation
There are no consistent recommendations for postoperative surveillance intervals for rectal cancer in the major guidelines. Knowledge about recurrence hazards can help develop appropriate surveillance schedules. This study aimed to investigate transitions in recurrence hazard and peak recurrence time in patients...
Zhi-Fang Zheng, Xiao-Jie Wang, Hong-Feng Pan et al.· BMC Cancer· 0 citations
Abstract Background Long-term outcomes and preoperative predictors after organ-sparing transanal endoscopic microsurgery (TEM) for rectal cancer remain incompletely defined. We assessed overall survival (OS), disease-free survival (DFS), and preoperative predictors. Methods Consecutive patients undergoing TEM with orga...
A. Arezzo, C. A. Ammirati, Giovanni Distefano et al.· MITAT. Minimally invasive th...· 0 citations
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