A systematic review of psychometric properties of physical fitness and physical functioning outcome measures applied in adult people with hemophilia
Abstract
ABSTRACT Introduction: Psychometric properties of clinical measurement instruments are crucial because they indicate the quality, reliability, and validity of data collected in clinical settings as well as how accurately and consistently a tool measures change. The aim was to systematically review and report the measurement properties of performance-based (PerFOMS) or clinician-reported (ClinROM) outcome measurement instruments (OMIs) in adult people with hemophilia (PwH). The second aim was to evaluate the methodological quality and the level of evidence of the reported measurement properties. Methods: Data search, extraction, and evaluation were conducted in accordance with the COSMIN methodology while following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Results: The literature search identified 2557 articles. After title and abstract screening, 166 were included for full-text screening. The 14 included studies reported measurement properties of 11 OMI’s (5 ClinROM & 6 PerFOMS). Reliability (intra-rater, inter-rater, or test-retest), measurement error, internal consistency, criterion validity, convergent validity, discriminant validity, and responsiveness were reported. The most reported measurement property was convergent validity. The OMI Hemophilia Joint Health Score (HJHS 2.1) fulfilled sufficient methodological quality for convergent validity and moderate Quality of Evidence (QE). None of the other included OMI’s reported sufficient measurement properties. Conclusion: Researchers and clinicians are challenged when comparing studies and selecting appropriate OMI’s when evaluating the functioning of adult PwH, due to unsatisfactory reporting of measurement properties, hampered methodological quality, and a low level of evidence. Therefore, studies investigating measurement properties of ClinROM and PerFOMS in adult PwH with rigorous methodology are required.