Low-molecular-weight Ulva lacinulata extract exhibiting anti-inflammatory and pro-autophagic activities in RAW 264.7 macrophages: a promising candidate for the development of active ingredients targeting low-grade inflammation
The potential of an extract from the green seaweed Ulva lacinulata as a safe and effective functional ingredient for the development of functional food and/or dietary supplements targeting chronic low-grade inflammation is highlighted.
Allium victorialis L. is a significant plant traditionally used as both food and medicine in Northeast China. However, the structural and functional studies of its polysaccharide components remain limited. In the present study, we investigated the anti-inflammatory potential of AVP-1-2 (DP 27), an inulin-type fructan i...
Xinyang Guo, Xiaoxiao Xiong, Xue-Qi Wang et al.· Plants· 0 citations
Black goji berry (Lycium ruthenicum Murr.) has been recognized for its immune-regulating and anti-cancer potentials, but its key active components and underlying mechanisms remain unclear. Here, we applied LC–MS/MS to characterize the metabolite profile of L. ruthenicum and performed in vitro assays to evaluate its ant...
Lei Jiang, Ji-Deng Ma, Zhi-Yuan Li et al.· Frontiers in Nutrition· 0 citations
This study highlights WSCE as a potential anti-dermatitis agent, suppressing pro-inflammatory mediators in T+I-stimulated keratinocytes via MAPK and NF-κB regulation and position WSCE as a promising candidate for ISD management.
The ethanolic extract of SMS attenuated LPS-induced inflammatory and oxidative stress responses in RAW 264.7 macrophages, suggesting effects may be associated with the suppression of inflammatory mediator production, reduction in the cellular oxidative stress burden and modulation of proteins involved in cellular stres...
Nianshou Zhao, Hongya Li, Peng Ji et al.· Antioxidants· 0 citations
Jing Guan Fang (JGF) is a traditional multi-herb formula used for hyperinflammatory conditions associated with severe viral infections; however, its protein-level effects in macrophage-mediated inflammation remain incompletely characterised. In this study, we combined ultra-performance liquid chromatography–quadrupole...
S. Yeon, Muhammad A. Alsherbiny, Yu-Ting Sun et al.· Antioxidants· 0 citations
Plant-derived natural products are essential and prominent contributors to drug discovery, especially as anticancer agents. Medicinal plants used in alternative therapy are often obscured by poor definitions of the underlying mechanisms behind their bioactivity. In this study, we investigated the cytotoxic and mechanis...
Saheed O Anifowose, Mobarak S. Al Mosallam, E. Bahattab et al.· Biomolecules· 0 citations
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