Oct 2026· ACS Applied Nano Materials· 0 citations· 58 references
TL;DR
In vitro experimental results indicated that the drug-loaded Fe3O4-NCNCs have considerable anti-tumor activity, suggesting Fe3O4-NCNC as a superior drug delivery platform.
Abstract
Nitrogen-doped carbon nanotube cups (NCNCs) exhibited significant potential as drug carriers owing to their unique cup-shaped and hollow nanostructures. To improve the biocompatibility of individual NCNCs, this study employed a bath sonicator and performed a methodical examination of ultrasonic frequency to optimize oxidation and separation efficiency. The NCNCs were further decorated with iron oxide nanoparticles (Fe3O4-NPs) via a co-precipitation method to impart magnetic property to this NCNC-based composite. The biocompatibility of Fe3O4-NCNCs was further confirmed by exposing the composites to hydrogen peroxide (H2O2), triggering the Fenton reaction to achieve degradation. Ultimately, the practicality of Fe3O4-NCNCs as drug delivery carriers was demonstrated by loading the nanocomposites with the ferroptosis inducer RSL3. The in vitro experimental results indicated that the drug-loaded Fe3O4-NCNCs have considerable anti-tumor activity, suggesting Fe3O4-NCNC as a superior drug delivery platform.
Mesoporous cerium oxide (CeO2) decorated nickel-based metal–organic framework (Ni-MOF) composites were synthesised by varying the CeO2 : Ni-MOF weight ratios, using ratios of 1 : 8, 2 : 8 and 3 : 8, following the optimization process. The corresponding composites are denoted as NC1, NC2 and NC3, respectively. The struc...
This work establishes a structure-guided design for carbon-based nanozymes and provides a safe, efficient platform for offering a non-antibiotic strategy to mitigate the risk of drug resistance.
Meng-Yao Yang, Jing-Tao Song, Xin Wang et al.· Journal of Colloid and Inter...· 0 citations
Polymer electrolyte membrane fuel cells (PEFCs) have garnered significant attention as energy conversion devices due to high efficiency and environmental benefits. However, the high cost and susceptibility to corrosion of platinum-based catalysts, widely used in PEFCs, remain major barriers to their development. In t...
Manganese ferrite (MnFe2O4) is a promising electrode material because of its redox-active Mn and Fe centers, chemical stability, and tunable spinel structure. However, its practical use in electrochemical sensing may be limited due to its poor electrical conductivity, particle aggregation, and limited access to active...
Khursheed Ahmad, S. Vignesh, Vinay Kumar Tripathi et al.· Analytical Methods· 0 citations
It is demonstrated that dopant-engineered MNPs combined with a ME carrier can provide a versatile platform for integrating magnetic hyperthermia potential, T2-weighted MRI contrast enhancement, and controlled chemotherapeutic delivery within a single nanostructured system.
Mirela Nistor, D. Ghercă, C. Uritu et al.· Nanomaterials· 0 citations
Biocompatible metal oxide nanoparticles (NPs) are promising materials for biointerfaces, wound healing, and theranostic applications owing to their multifunctional properties. Here, we report manganese‐doped TiO2 (Mn‐doped TiO2) nanozymes that integrate the chemical stability and biocompatibility of TiO2 with the redox...
Filip Kozłowski, Nayoung Kim, Hyunwoo Choi et al.· Advanced Materials Interface...· 0 citations
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