GLP‐1 Receptor Agonist–Based Prandial Insulin De‐Intensification in Outpatients With Type 2 Diabetes Receiving Basal–Bolus Insulin Therapy or Multiple Daily Injections: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials

Abstract

This systematic review and meta‐analysis aimed to compare GLP‐1 receptor agonist (GLP‐1RA)‐based prandial insulin de‐intensification with continued basal–bolus insulin therapy (BBI) or multiple daily injections (MDI) in adult outpatients with type 2 diabetes receiving established BBI/MDI at randomisation.