Available evidence supports a multidisciplinary framework in which male fertility is interpreted within the broader context of systemic and functional health, and integrating reproductive evaluation with metabolic and musculoskeletal assessment may improve early risk stratification and facilitate more targeted therapeutic strategies.
This narrative review synthesizes current evidence supporting osteosarcopenia as an integrated musculoskeletal syndrome, with a particular focus on biomechanical loading, biochemical crosstalk, and inflammatory signaling.
Jeonghyeon Seo, Sang Hoon Hwang, J. Yoon et al.· Journal of Korean Neurosurgi...· 0 citations
The coordinated optimization of nutrition, exercise, and circadian health, with attention to regularity and timing, may offer complementary benefits exceeding single-domain interventions.
Sih-Yung Lee, Choon Young Kim· Aging and Disease· 0 citations
Key mechanistic evidence demonstrating how targeted GM interventions and structured exercise regimens may synergistically counteract muscle decline is explored, to support the development of innovative therapeutic approaches combining exercise and GM modulation to improve muscle health, functional independence, and hea...
Ana Sofia Merelim, Ângelo P. Santos, Rodrigo Zacca et al.· Sport Sciences for Health· 0 citations
By integrating metabolic, endocrine, and epigenetic perspectives, this review provides a mechanistic framework to better understand obesity-related male infertility and to inform future clinical and translational research.
This review defines the pathophysiological mechanisms that connect metabolic syndrome to male infertility by focusing on how obesity-related inflammation affects male reproductive health.
Shreeram Behera, Koushik Bhattacharya, S. Jal et al.· Biomedicines· 0 citations
Available evidence supports physical activity and structured exercise as important components of PMOS management, particularly for improving insulin sensitivity, body composition, cardiometabolic risk markers, and, in some studies, menstrual cyclicity and ovulatory function.
Xin-Jian Huang, Zhi Chen, Li-Yi Zhang et al.· Frontiers in Endocrinology· 0 citations
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