Skip to content

Design and Synthesis of Dual Fluorophore for Detection of Fe3+ and Hg2+ in Aqueous Solution Through Fluorescence “Turn‐Off”

Oct 2026 · Luminescence (Chichester, England Print) · Vol 41 · 0 citations · 50 references
Medicine

Abstract

Here, we report the design and synthesis of a new bicyclic compound 6, annulated with benzene and the 8‐hydroxyquinoline fluorophore. The probe exhibits a moderate aggregation‐induced emission (AIE) behavior upon the addition of water up to 17%. Furthermore, the probe exhibits a highly selective fluorescence turn‐off response toward Fe3+ and Hg2+ ions in a DMSO/H2O (83:17, v/v) solution over a range of other competitive metal ions. The probe displayed low detection limits of 3.69 μM for Fe3+ and 6.08 μM Hg2+. Probe 6 shows a fast recognition time of ions and can monitor Fe3+ and Hg2+ ions in real time. The sensing mechanism is thoroughly investigated by time‐dependent 1H NMR studies, which indicate coordination interactions between the quinoline framework and the metal ions. The probe demonstrates high sensitivity and dual‐selectivity toward metal ion sensing, making it a valuable tool for monitoring the environment.

View source

Similar papers

Open access Sep 2026

A “turn-on” Fluorescent Probe with Ions-induced ESIPT for the Detection of Cd2+ and Zn2+

Developing an Aggregation-Induced Emission Enhancement (AIEE) type probe with enhanced emission through metal ion-induced methods has been a significant challenge. In this work, we synthesized an AIEE fluorescent chemosensor P1 via a Schiff base reaction by 8-hydroxyquinoline-2-carbaldehyde and 2,4-difluorophenylhydraz...

Mei Yu, Na-Na Mu, Qing-Yi He et al. · 0 citations
Sep 2026

Synthesis, spectroscopic and DFT investigation of a dual-fluorophore methylene blue-naphthalimide probe for selective Cu2+ ions sensing and HeLa cell imaging.

A new fluorescent probe based on fluorophores methylene blue and 1,8-naphthalimide is designed, synthesized, and utilized for the specific detection of Cu2+ ions in physiological conditions demonstrating that MB-M is a promising fluorescent probe for Cu2+ ions ion detection.

S. M. Gomha, Wajeeha Zareen, Mostafa A. Ismail et al. · 0 citations
Sep 2026

A multifunctional bisphenol A-based dual-fluorophore fluorescent probe for the detection of Fe3+: practical applications in water, fingerprint, and cell imaging.

BONR, a newly developed fluorescent probe, was prepared through the fusion of bisphenol A, dicyanoisophorone, and Rhodamine ethylenediamine. This probe enables the specific detection of Fe3+ ions, resulting in a synergistic enhancement of both its spectral properties and practical application. In an EtOH/HEPES (1:1, v/...

Yi-Han Yang, Feng-Jun Yan, Xiao-Xia Cheng et al. · 0 citations
Open access Oct 2026

A multifunctional bishydroxycoumarin conjugate exhibiting AIE characteristics and tandem Co2+/ATP detection with logic gate operations, on-site sensing and bioimaging applications

An efficient coumarin-based fluorescent probe, HCPD, was synthesized via condensation of 7-diethylamino-4-hydroxycoumarin aldehyde with o-phenylenediamine. The structure of the probe was confirmed by FT-IR, NMR and HRMS studies. The probe, HCPD exhibited aggregation-induced emission (AIE) characteristics in a THF-water...

Rajendran Kishore Kumar, Suryaa Manoharan, Ekambaram Perumal et al. · 0 citations
Open access Aug 2026

From solutions to living systems: a colorimetric and “turn-on” chemosensor for Co2+ with paper-strip and bioimaging applications

5-(4-Chlorophenoxy)-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde (PYA), a pyrazole-based fluorescent chemosensor, was synthesised and studied for the selective detection of Co2+ ions. With exceptional selectivity over other metal ions that are relevant to biology and the environment, the sensor displays a clear “turn-o...

A. R. Nesaragi, Jyoti Nagalik, Thakur Gurjeet Singh et al. · 0 citations
Open access Sep 2026

A Novel Boranil-Based Colorimetric and Fluorescence Quenching Probe for Selective Detection and Bioimaging of the Fe3+ ion

A novel, readily synthesizable boranil-based chemosensor, HSR, was structurally and spectroscopically characterized by single-crystal X-ray diffraction, IR spectroscopy, 1H, 13C, and 11B NMR spectroscopy, and high-resolution mass spectrometry (HRMS). HSR exhibited highly selective colorimetric and fluorescence response...

Darakhshan Parveen, Saumya Singh, Avadhesh Pratap Singh et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.