Aug 2026· Machine Learning for Biomedical Imaging· 0 citations· 25 references
EngineeringComputer Science
TL;DR
This work creates the first publicly available resource for predicting left ventricular ejection fraction (EF) from parasternal long-axis (PLAX) echocardiography by leveraging a time-based correlation between clinical notes and echocardiographic videos and fine-tuning view classifiers and proxy labeling.
Abstract
We present, to the best of our knowledge, the first publicly available resource for predicting left ventricular ejection fraction (EF) from parasternal long-axis (PLAX) echocardiography. Because no PLAX–EF datasets previously existed, our work focuses on an innovative data generation strategy to overcome this scarcity. By leveraging a time-based correlation between clinical notes and echocardiographic videos, combined with fine-tuning view classifiers and proxy labeling, we created a labeled dataset of over 25,000 PLAX videos. This enables us to train the first reproducible PLAX EF model, achieving a mean absolute error (MAE) of 6.86%. Given that apical four-chamber (A4C) methods, the clinical standard, report MAE values of 6%-7%, our results demonstrate that EF estimation from PLAX views is both feasible and clinically relevant. This surpasses the performance of existing methods and provides a clinically relevant solution for situations where apical views may not be feasible. Going further, we demonstrate that combining PLAX and A4C predictions via simple unweighted late fusion improves both single-view baselines to a 6.37% MAE, underscoring the value of multi-view integration. To promote continued research, we release the dataset labels, trained models, and runnable demos on GitHub, Hugging Face, and Google Colab: https://github.com/Jeffrey4899/PLAX_EF_Labels_202509
BACKGROUND
Accurate assessment of left ventricular outflow tract (LVOT) gradients is critical for hypertrophic cardiomyopathy management, yet Doppler-based measurements are technically demanding and require expertise. The objective of this work was to develop a multi-view deep learning model capable of classifying LVOT...
O. Crystal, J. Farina, I. Scalia et al.· Circulation Cardiovascular I...· 0 citations
Cross-dataset generalisation remains a major barrier to clinical deployment of echocardiographic left ventricular segmentation, yet the sources of this shift are rarely disentangled. We examined whether transfer degradation could be estimated before deployment using handcrafted ultrasound descriptors, VAE latent featur...
Deep video networks estimate left ventricular ejection fraction (EF) from echocardiograms with expert-level accuracy, but the compute cost of running them is rarely reported. This leaves anyone building a handheld or bedside tool without clear guidance on what to deploy. We measured the accuracy-versus-compute tradeoff...
A. Pandey, K. Sharma, A. Shah· medRxiv· 0 citations
Abstract Aims Hypertrophic cardiomyopathy (HCM) remains underdiagnosed due to limited access to expert imaging. We developed and validated a deep-learning (DL)-based echocardiographic model adaptable to point-of-care ultrasound (POCUS) for scalable HCM screening. Methods and results We retrospectively analysed 134 956...
N. Karra, Y. Klempfner, Viana Copeland et al.· European Heart Journal - Dig...· 0 citations
This study implemented strict subject-disjoint partitioning to eliminate data leakage, and simultaneously introduced cross-frame case aggregation to emulate the multi-frame visual synthesis process of expert echocardiographers, suggesting that the proposed workflow has the potential to serve as an adjunctive tool for s...
Tao Zhang, Peipei Zhang, Qing-Yuan Zhang et al.· IEEE Access· 0 citations
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