transanal endoscopic microsurgery for rectal cancer represents a risk factor for an increased abdominoperineal resection rate

Oncologic safety of transanal total mesorectal excision after neoadjuvant chemoradiotherapy for advanced rectal cancer: long-term outcomes compared with robot TME.

Functional and oncological outcomes after laparoscopic versus open total mesorectal excision for rectal cancer: a propensity score-matched study

While minimally invasive surgery and traditional open surgery are generally equivalent in terms of oncological outcomes for rectal cancer, maintaining postoperative quality of life is increasingly important. Low anterior resection syndrome is a distressing complication following sphincter-preserving surgery that se...

Short- and Long-Term Outcomes of Transanal Total Mesorectal Excision for Rectal Cancer: A Single-Center Retrospective Study of 100 Patients.

PURPOSE Transanal total mesorectal excision (TaTME) has been introduced to facilitate distal rectal dissection; however, concerns regarding its oncological safety persist. This study evaluated the outcomes of TaTME in a real-world setting. METHODS Between 2019 and 2025, 123 patients underwent TaTME at our institution...

Short‐Term Outcomes of Transanal Total Mesorectal Excision for Rectal Cancer: A Multicenter Propensity Score‐Matched Analysis Comparing Patients With and Without Preoperative Neoadjuvant Therapy

ABSTRACT Aim To evaluate the association between preoperative neoadjuvant therapy and short‐term outcomes of transanal total mesorectal excision for rectal cancer. Methods We retrospectively analyzed patients who underwent transanal total mesorectal excision at 26 Japanese institutions between 2012 and 2019. Patients w...

Transanal local excision reduces surgical burden without evidence of increased recurrence in lower rectal GIST: a multicenter inverse probability of treatment weighting analysis.

BACKGROUND Lower rectal gastrointestinal stromal tumors (rGISTs) pose a surgical challenge, as complete resection must be balanced against anorectal function preservation. Transanal local excision (taLE) may offer a less invasive alternative to transabdominal laparoscopic radical resection (tlRR), but comparative evide...

Radiotherapy-to-Surgery Interval After Induction Total Neoadjuvant Therapy for Rectal Cancer: Perioperative Outcomes and Oncologic Quality of Total Mesorectal Excision.

BACKGROUND The interval from radiotherapy completion to surgery may affect pelvic fibrosis, operative difficulty, postoperative morbidity, and quality of rectal cancer resection. In total neoadjuvant therapy (TNT), however, this interval has different clinical content according to treatment sequence. We evaluated wheth...