Hybrid geometric and evolutionary optimization framework for radiosurgery planning: isocenter selection and angle optimization for multiple brain metastases.

Geometric and dosimetric effects of an automated clustering and plan optimization pipeline for multiple brain metastasis radiosurgery

Abstract Background Treating multiple brain metastases simultaneously with single‐isocenter multi‐target (SIMT) stereotactic radiosurgery (SRS) can streamline treatment planning and delivery. However, it can also result in targets at large distances from the isocenter, increasing sensitivity to rotational setup errors...

Dosimetric comparison of the anisotropic analytical algorithm and Acuros XB for single-fraction cranial stereotactic radiosurgery with a 6 MV flattening filter-free beam

Stereotactic radiosurgery delivers an ablative single-fraction dose to small intracranial targets, and the reported dose depends on the calculation algorithm. This exploratory case series quantified the change in reported dosimetry when plans clinically finalised with the anisotropic analytical algorithm (AAA) were rec...

End to end dosimetric and geometric verification of single isocenter multitarget stereotactic radiosurgery using an anthropomorphic phantom: external audit validation.

Dosimetric study of split-arc technique based on personalized collimator optimization in VMAT for multiple brain metastases.

Balancing dosimetric quality and efficiency, the 6-split arc (6sA) strategy is recommended as the preferred protocol for MBM.

Integrated isocenter and sector duration optimization (ISDO) for gamma knife radiosurgery

An integrated isocenter and SDO framework (ISDO) that replaces heuristic isocenter placement with a dose-driven joint ISDO and achieved more efficient and conformal GK plans than current clinical GK treatment planning approaches is introduced.

Dose accuracy evaluation of multi-leaf collimator modeling in single-isocenter multi-target stereotactic radiosurgery

Background and purpose Accurate modeling of multi-leaf collimators is critical for dose calculation in stereotactic radiosurgery (SRS), where steep dose gradients and small target volumes amplify modeling uncertainties. This study compared enhanced leaf modeling and dosimetric leaf gap approaches using two clinically i...