Jan 2026· Clinics· Vol 81, pp. 101109· 0 citations· 49 references
Medicine
TL;DR
Findings support new public health strategies for Afro-Brazilian and admixed populations in admixed populations and pose diagnostic and therapeutic challenges in admixed populations.
Abstract
Highlights • CKD remains a major health burden in Latin America and middle-income regions.• APOL1 kidney disease poses diagnostic and therapeutic challenges in admixed populations.• Studies on APOL1 kidney disease are scarce in admixed and Afro-Brazilians.• Findings support new public health strategies for Afro-Brazilian and admixed populations.
CKD is a major complication of T2DM and a leading cause of end‐stage kidney disease. Because urinary albumin‐to‐creatinine ratio (UACR) and eGFR have recognized limitations, additional biomarkers may help characterize kidney dysfunction. HCY is frequently elevated in CKD and may reflect pathways of renal injury. We eva...
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Kidney disease is a global public health problem, affecting over 750 million persons worldwide. In many settings, rates of kidneydisease and the provision of its care are defined by socio-economic, cultural, and political factors leading to significant disparities.World Kidney Day 2019 offers an opportunity to raise aw...
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