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An integrative review of APOL1 kidney disease with a focus on the Brazilian population

Jan 2026 · Clinics · Vol 81, pp. 101109 · 0 citations · 49 references
Medicine

TL;DR

Findings support new public health strategies for Afro-Brazilian and admixed populations in admixed populations and pose diagnostic and therapeutic challenges in admixed populations.

Abstract

Highlights • CKD remains a major health burden in Latin America and middle-income regions.• APOL1 kidney disease poses diagnostic and therapeutic challenges in admixed populations.• Studies on APOL1 kidney disease are scarce in admixed and Afro-Brazilians.• Findings support new public health strategies for Afro-Brazilian and admixed populations.

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