TL;DR
It is reported that the rs763780 polymorphism may be associated with risk of developing gastric cancer in the population studied, particularly in alcohol drinkers.
It is suggested that SYNE1 rs2295190 may be associated with OSCC progression rather than overall disease susceptibility, particularly in the context of betel quid exposure.
Background/Aim: Colorectal cancer is the second most common cancer in women and the third most common in men. It is the third leading cause of cancer death worldwide. Statistics suggest a worrying increase in the incidence of this cancer in the coming years. Many factors, including family history, age, smoking habits a...
Single nucleotide polymorphisms (SNPs) in the interleukin-17F (IL-17F) gene may modulate inflammatory responses, with distinct effects on inflammation and tumour progression. Helicobacter pylori infection, a Group 1 carcinogen, is strongly associated with gastric cancer (GC) development. This study investigated the inf...
Background The CYP1A1 Ile462Val (rs1048943 A > G) polymorphism has been associated with susceptibility to several cancers, but its role in laryngeal cancer remains unclear. This study investigated the association between rs1048943 and laryngeal cancer risk in a Sudanese population. Methods A hospital-based case–con...
Background/Aim: Interleukin-4 (IL-4) is a key T-helper 2 cytokine involved in immune regulation, allergic responses, and hematological malignancies. Although aberrant IL-4 expression has been implicated in acute lymphoblastic leukemia (ALL), the contribution of IL-4 genetic polymorphisms to childhood ALL susceptibility...
Background/Aim: Matrix metalloproteinase-13 (MMP-13) plays an important role in extracellular matrix remodeling and has been implicated in the susceptibility and progression of several malignancies. However, the contribution of MMP-13 genetic polymorphisms to childhood acute lymphoblastic leukemia (ALL) remains unknown...
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