Platelet-Rich Plasma in Human Reproduction: A Review of the Evidence in Endometrium, Ovary, and Male Infertility.

Abstract

Although platelet-rich plasma (PRP) is an experimental therapeutic approach under investigation in different areas of medicine, several questions remain unresolved, and its use in human reproduction is still considered experimental. This limitation stems mainly from the scarcity of robust clinical studies and the heterogeneity of PRP preparation and application methods, factors that hinder comparisons among studies and contribute to inconsistent results. This narrative review aimed to evaluate the different applica-tions of PRP in reproductive medicine and its effects on patients with infertility. The findings suggest that PRP may be associated with improved pregnancy rates in some studies compared with control groups and may also favor outcomes in assisted reproduction treatments in humans.