Oct 2026· The Neurohospitalist· pp.
19418744261500506
· 0 citations· 6 references
Medicine
TL;DR
This case highlights an unusual extramedullary trigeminal nerve root lesion as a potential manifestation of NMOSD.
Abstract
A 62-year-old woman presented with left-sided facial and intraoral sensory disturbance due to a relapse of aquaporin-4 immunoglobulin G-positive neuromyelitis optica spectrum disorders (NMOSD). Brain MRI demonstrated an isolated lesion in the left extramedullary trigeminal nerve root. Although various diseases should be considered in the differential diagnosis of isolated trigeminal neuropathy, the trigeminal nerve root may represent a target during NMOSD relapses. This case highlights an unusual extramedullary trigeminal nerve root lesion as a potential manifestation of NMOSD.
Neuromyelitis optica spectrum disorder (NMOSD) rarely presents with corticalleptomeningeal involvement. A 47-year-old woman with aquaporin-4 immunoglobulin G (AQP4-IgG)-positive NMOSD developed acute headache, seizures, motor aphasia, and worsening right arm weakness. Brain magnetic resonance imaging revealed a tumefac...
This case suggests that marked cranial nerve hypertrophy may be clinically unapparent in some hereditary polyneuropathies and supports future correlation of temporal bone pathology with imaging and genotype in confirmed cases.
Yassine Balhi, Syed Ameen Ahmad, Amanda M. Lauer et al.· The Laryngoscope· 0 citations
Cranial bone disorders are a rare cause of secondary trigeminal neuralgia (TN), producing pain through progressive compression of the trigeminal nerve. We report a 46-year-old man with autosomal dominant osteopetrosis type 1 with left-sided refractory TN. Osteosclerosis of the petrous bone caused medial displacement...
S. Hendrickx, R. Dammers, V. Volovici· Acta Neurochirurgica· 0 citations
Introduction: Trigeminal neuralgia (TN) is a paroxysmal neuropathic facial pain that is classified as classical, idiopathic or secondary. Space-occupying lesions account for approximately 4–6% of TN presentations, and meningioma is one of the most frequent culprits. The coexistence of TN with meningiomatosis—two or mor...
Luh Wayan Puspa Ningsih, Ida Bagus Kade Satyagraha· International journal of med...· 0 citations
Neurofibromatosis type 1 is a widely known phakomatosis with highly variable manifestations. However, its presentation with hemicerebral atrophy resulting from an intracranial vasculopathy is uncommon, yet it poses a major health threat. We hereby report the case of a 6-year-old boy with the clinical features of Neurof...
Bethlehem Abera, Bethelhem Belachew, H. Ahmed et al.· Radiology Case Reports· 0 citations
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