TL;DR
This chapter details how enhancer and gene body methylation correlate with transcriptional activity and how transcription factors, like Early Growth Response 1, recruit demethylation machinery during development.
This chapter focuses on epigenetic factors that are involved in DNA methylation and histone modifications, known as "writers, readers, and erasers/modifiers," and a brief section is also included on regulatory RNA molecules that may impact gene expression.
DNA modifications are epigenetic marks added directly to DNA bases that can stably or dynamically regulate gene expression, allowing cells to maintain their identity while also having flexibility to adapt to changes in their environment1. Aging is often thought to disrupt this regulation, causing cells to lose their id...
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