Primary Ciliary Dyskinesia with Secondary Pseudomonas aeruginosa Infection in a Dog: Endoscopic and Diagnostic Findings

Abstract

Simple Summary A young dog was presented with a lifelong history of chronic respiratory signs that partially improved with antibiotic treatment but repeatedly returned after therapy was stopped. To investigate the underlying cause, endoscopic examination of the respiratory tract was performed, allowing the collection of several biological samples for further analysis. Ultrastructural examination and microbiological testing led to a diagnosis of primary ciliary dyskinesia associated with Pseudomonas aeruginosa infection. Primary ciliary dyskinesia is a rare congenital disorder characterized by abnormalities in the structure and movement of cilia, including those lining the respiratory tract. These cilia play an important role in protecting the airways by removing mucus, microorganisms, and other inhaled particles. When their function is impaired, affected animals may develop recurrent or persistent respiratory infections. This case highlights the importance of clinical history, endoscopic examination and transmission electron microscopy in the diagnosis of primary ciliary dyskinesia.