Sep 2026· Glavvrač (Chief Medical Officer)· pp. 61-74· 0 citations· 16 references
TL;DR
The authors examine the etiological profile (dominated by Trichophyton rubrum), risk factors, and key mechanisms of resistance, including the spread of Trichophyton indotineae, including the spread of Trichophyton indotineae.
Abstract
This article reviews current strategies for the treatment and prevention of onychomycosis, a chronic fungal nail infection, the global prevalence of which reaches 20% or higher in high-risk groups (the elderly, patients with diabetes mellitus, and the immunocompromised). The authors examine the etiological profile (dominated by Trichophyton rubrum), risk factors, and key mechanisms of resistance, including the spread of Trichophyton indotineae. Strategies for topical, systemic, and combination therapies are analyzed in detail, alongside criteria for drug selection based on the clinical form of the disease and the patient's comorbid conditions. Particular attention is paid to essential components of successful prevention and treatment, such as footwear disinfection and non-pharmacological methods like laser therapy, photodynamic therapy, surgical nail plate removal, medical instrument-based pedicures, etc. The importance of a comprehensive, personalized approach and laboratory monitoring of cure status to ensure lasting results and prevent recurrence is emphasized.
This article presents a clinical-pharmacological overview of current approaches to treating onychomycosis, the most common fungal nail infection, with a global prevalence of approximately 4–5.5%. It examines the epidemiology, etiological profile (characterized by the predominance of Trichophyton rubrum and an increasin...
M. Maksimov, Yu. A. Akulinina, A. D. Sidorova et al.· Glavvrač (Chief Medical Offi...· 0 citations
According to epidemiological data, superficial mycoses may affect approximately 20–25% of the global population. They account for 37–40% of all dermatological diseases, which further underscores the need for discussion and development of preventive strategies both within the specialty and in an interdisciplinary contex...
E. Kasikhina, M. Ostretsova, S. С. Ismatullaeva· Meditsinskiy sovet = Medical...· 0 citations
The modern course of mycoses is determined by a complex of factors, including irrational therapy, concomitant somatic pathology, and the development of drug resistance. Intertriginous mycoses are characterized by acute inflammatory symptoms and are often complicated by bacterial infection, which can lead to chronicity...
M. Tlish, M. Shavilova, F. Psavok· Meditsinskiy sovet = Medical...· 0 citations
Onychomycosis is a chronic and recurrent nail infection whose worldwide prevalence continues to increase, affecting 5%-10% of the general population and up to 50% of individuals older than 70 years. Despite the availability of multiple effective therapeutic options, current management practices remain suboptimal, and r...
L. N. Campoamor, M. Iglesias-Sancho, E. J. Blázquez· Actas Dermo-Sifiliográficas· 0 citations
Onychomycosis is a common chronic fungal infection of the nail unit that may be associated with significant functional impairment and impaired quality of life. Systemic antifungal drugs remain the cornerstone of treatment for moderate-to-severe disease, with continuous oral terbinafine and pulse itraconazole being the...
A. Koshy, Ashwin Kamath· European Journal of Clinical...· 0 citations
Inflammatory and infectious diseases of the oropharynx and oral cavity are among the most common reasons for visiting primary care outpatient specialists. The key challenge is the excessively frequent use of systemic antibacterial agents, although in most cases the disease has a viral etiology. This practice directly c...
S. V. Ryazantsev, S. S. Vysockaya, O. S. Donskaya et al.· Consilium Medicum· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
