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Early-life tobacco smoke exposure and incident rheumatoid arthritis: mediated by allostatic load and joint effects with polygenic risk.

Wei Huang Xing-Yu Wan Yi-Xu Wang Yi-Han Hu Shi-Hao Jing Yi Zhang Pan Ke Dan-Kang Li Chao Zhang Rui-Xue Leng Qi Wang Dong-Sheng Di

Sep 2026 · Rheumatology · Vol 65 · 0 citations

Medicine

TL;DR

Early-life tobacco smoke exposure elevates RA risk in adulthood, with limited mediation by AL and modification by genetic predisposition.

DOI PubMed Semantic Scholar

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