Associations between Heavy Metals and Metalloids and Hepatic Fibrosis Risk in Chinese Adults: A Potential Modifying Effect of Thyroid Hormones.

Selenium predominance in heavy metal mixtures is associated with hyperuricemia in Chinese adults: the role of insulin resistance

Insulin resistance might be a crucial mediated pathway between Se and outcomes and three multi-pollutant models revealed positive associations between metal mixtures and SUA as well as HUA, with Se being the primary contributor.

Associations of serum metals and metalloids with noninvasive hepatic steatosis indices: a seasonal repeated-measures metabolome-wide study.

BACKGROUND Evidence linking metals and metalloids to hepatic steatosis rests mainly on single measurements. We examined these associations and accompanying metabolic pathways using four seasonal repeated serum measurements. METHODS This Hefeng cohort included 172 adults with 541 observations after excluding visits wi...

Metals and metalloids signatures in early pregnancy suggest cadmium and arsenic as major mixture components associated with gestational diabetes mellitus risk.

Pregnancy is a vulnerable window for environmental pollutant exposure, yet the contribution of metals and metalloids (metal(loid)s) to gestational diabetes mellitus (GDM) remains insufficiently characterized. This prospective cohort study evaluated whether early-pregnancy urinary metal(loid)s were associated with subse...

Associations of serum trace elements with liver fibrosis in adults: integration of metabolomics and network toxicology analysis.

The association between multiple trace elements exposure and liver fibrosis, along with potential biological correlates, remains poorly understood. We conducted a longitudinal panel study among 205 adults with four repeated visits in Enshi, China. Liver stiffness measurement (LSM) and controlled attenuation parameter (...

Association of Combined Exposure to Polycyclic Aromatic Hydrocarbons, BTX and Metals with Metabolic Syndrome Risk.

Mixed exposure to PAHs, BTX, and metals increased MetS risk more than single pollutants, highlighting their importance for future occupational health monitoring and risk management.

Associations of blood and urinary heavy metals with obesity risk among children: NHANES 2015-2020.