Outcomes and Prognosis of Acute Liver Failure: Insights from a Busy Liver Centre at Max Healthcare

How to manage: acute-on-chronic liver failure

Acute on chronic liver failure has emerged as a distinct clinical entity over the past few decades. While mortality remains highest for patients who develop liver and multiple non-liver organ failures, earlier recognition of the syndrome, including identification and management of precipitating factors, as well as a sy...

Outcomes and Risk Factors of Pediatric Liver Transplantation in A Resource‐Limited Setting: A 15‐Year Cohort Study

Liver transplantation is the definitive treatment for end‐stage liver disease in children. Despite improved survival, mortality and acute rejection remain significant. Evidence from developing countries is limited; therefore, this study aimed to evaluate one‐year mortality, acute rejection, and associated risk factors...

Higher model for end-stage liver disease excluding international normalized ratio scores predict worse kidney graft outcomes in simultaneous heart-kidney transplantation

BACKGROUND While the model for end-stage liver disease excluding international normalized ratio (MELD-XI) is known to be associated with adverse outcomes following cardiac surgery and heart transplantation, its predictive value in outcomes of simultaneous heart–kidney transplant (SHKT) remains unclear. To identify a re...

World Journal of Transplantation

Preconditioning with sufentanil confers protective effects in transplantation by attenuating hepatic ischemia-reperfusion injury

Hepatic ischemia-reperfusion injury (HIRI) is a significant contributor to liver dysfunction and failure following liver transplantation and hepatic surgical procedures. With the increasing global incidence of end-stage liver disease necessitating transplantation, strategies to mitigate HIRI have become important. Ferr...