Sep 2026· Veterinary Record Case Reports· Vol 14· 0 citations· 18 references
TL;DR
An 8‐year‐old, female, entire toy poodle presented with external ophthalmoplegia, facial and laryngeal paralysis and megaoesophagus, and was ultimately euthanased due to ongoing regurgitation resulting in severe aspiration pneumonia.
Abstract
An 8‐year‐old, female, entire toy poodle presented with external ophthalmoplegia, facial and laryngeal paralysis and megaoesophagus. Neostigmine methylsulfate administration yielded a positive response, and acetylcholine receptor autoantibody titres confirmed a diagnosis of myasthenia gravis. No cranial mediastinal mass was identified on thoracic radiographs. The patient initially demonstrated a favourable response to treatment with an acetylcholinesterase inhibitor, but was ultimately euthanased due to ongoing regurgitation resulting in severe aspiration pneumonia. No appendicular muscle weakness was noted at any point, including up to the time of euthanasia approximately 4 weeks after the initial onset of clinical signs. This is the first report of external ophthalmoplegia in a dog with focal myasthenia gravis.
Case Presentation: A 43-year-old woman was referred to investigate complaints of myalgia and weakness. Symptoms began at 8 years old, firstly in the right arm, followed by the right leg, both accompanied by localized warmth, erythema, allodynia, and edema, without preceding trauma. Two years later, the affected extremi...
Gustavo Freitas Alves de Arruda, A. Martins, Mateus Augusto Rangel Nunes et al.· ANPAbstract_CBN26· 0 citations
Abstract A late preterm newborn presented with paresis of the lower limbs with right-sided predominance, ipsilateral patellar areflexia and left-sided hyporeflexia, suggestive of myelitis, which was confirmed by magnetic resonance imaging. The diagnosis of congenital toxoplasmosis was confirmed through the presence of...
Martha Africano, Yuly Bayona, Diego Bravo et al.· Biomédica· 0 citations
We report a case of dermatomyositis in a 35-year-old woman with chronic right-sided hemiparesis, in whom cutaneous manifestations including Gottron papules were confined to the more functionally active left side, while the paretic right extremities were spared. PET-CT demonstrated asymmetric skeletal muscle FDG uptake...
J. Ishizaki, S. Yoshida, Katsuto Takenaka· British Journal of Dermatolo...· 0 citations
Case Presentation: A 26-year-old woman presented at age 15 with binocular diplopia, fluctuating bilateral ptosis, and dysphonia. Over the following 3-4 months, she developed progressive dysphagia with intermittent nasal regurgitation of liquids and weight loss. At age 20, she experienced a major event of pulmonary aspi...
Gustavo Freitas Alves de Arruda, Andréia Lira de Oliveira, V. F. Cury et al.· ANPAbstract_CBN26· 0 citations
Milroy disease is a rare hereditary lymphatic disorder caused mainly by VEGFR3 mutations and typically presents with lower limb edema. We report a severe unilateral case in a 6-month-old boy with massive right-leg elephantiasis that impaired motor development. Examination and lymphoscintigraphy confirmed lymphatic apla...
Y. Ismiarto, T. Kemal, Sudaryanto et al.· Frontiers in Surgery· 0 citations
Myasthenia gravis (MG) usually presents with fluctuating ocular or limb weakness; bulbar-respiratory–predominant disease is less common and easily misattributed to infection or gastrointestinal pathology. We report a 24-year-old man whose year-long dysphagia and intermittent breathlessness culminated in presumed severe...
Emmanuel Agyin-Frimpong· African Journal of Current M...· 0 citations
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