Findings suggest multiple factors influence G-tube timing and outcomes in patients with localized head and neck cancer undergoing definitive chemoradiation (dCRT).
Abstract
Background
G-tube placement timing remains poorly characterized in patients with localized head and neck cancer (HNSCC) undergoing definitive chemoradiation (dCRT).
Methods
We retrospectively analyzed 144 patients with HNSCC who received dCRT (2019-2024), categorized by "upfront" or "as-needed" G-tube strategy, to explore factors associated with timing and outcomes using propensity score weighting.
Results
Most patients were White (85%) and male (83%); median age was 63 years. Upfront G-tube placement occurred in 60 patients (42%) and was more common among women (64% vs. 37%, p = 0.015) and those with dysphagia (55% vs. 28%, p = 0.001) or receiving induction chemotherapy (71% vs. 38%, p = 0.023). dCRT duration, weight loss, ED visits, hospitalizations, ICU admissions, and survival did not differ. Upfront placement was associated with lower odds of chemotherapy modification (73% lower, p = 0.007) and fewer infusion clinic visits (average 3 fewer, p = 0.038).
Conclusion
These findings suggest multiple factors influence G-tube timing and outcomes, warranting prospective validation.
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BACKGROUND
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AIMS/OBJECTIVES
To compare survival outcomes between surgery and definitive chemoradiation therapy (CRT) in patients with locally advanced PSCC.
MATERIALS AND METHODS
Data on 1...
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BACKGROUND
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BACKGROUND
Body Mass Index (BMI) is a readily measured indicator of nutritional status; however, its impact on outcomes in head and neck cancer (HNC) patients remains understudied. This study evaluated the impact of pre-treatment BMI on toxicities and survival in such patients.
METHODS
This retrospective study includ...
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PURPOSE
To evaluate whether reducing overall treatment time (OTT) by shortening interventional radiotherapy (IRT; brachytherapy) duration affects outcomes in patients with locally advanced cervical cancer undergoing definitive chemoradiation.
METHODS AND MATERIAL
In this randomized clinical trial, conducted in 2016-2...
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