Abstract B155: Colorectal and lung cancer screening behaviors among breast cancer survivors

Abstract

Breast cancer survivors require ongoing surveillance because they remain at risk for recurrence and second primary cancers (SPCs). Adherence to recommended cancer screening guidelines is therefore an important component of survivorship care. Although survivors frequently interact with the healthcare system, evidence regarding their compliance and upkeep of age-appropriate preventive cancer screenings compared with women without a history of cancer remains limited. We examined association between history of breast cancer and adherence to recommended colorectal cancer (CRC) and lung cancer (LC) screening behaviors using a nationally representative U.S. population. We conducted a cross-sectional study using a 1:1 random sample of female respondents (breast cancer survivors vs. without a history of cancer) aged ≥40 years from the 2024 Behavioral Risk Factor Surveillance System. The exposure variable was breast cancer diagnosis (with a history of breast cancer or without a history of cancer). Outcomes were self-reported receipt of CRC (colonoscopy or sigmoidoscopy) and LC screening, both dichotomized as yes/no. Survey-weighted descriptive statistics were used to compare participant characteristics between breast cancer survivors and individuals without a history of cancer. Multivariable survey-weighted logistic regression models estimated adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for each screening behavior, adjusting for age, race/ethnicity, education, marital status, household annual income, health insurance, routine checkup, comorbidity count, health status, and having a regular healthcare provider. A total of 3,442 respondents were included in the study. Among these, 1,721 were breast cancer survivors. Compared with individuals without a history of cancer, breast cancer survivors were more likely to be older than 75 years (36.9% vs. 18.2%), be Non-Hispanic White (76.8% vs. 61.8%), have a regular health provider (98.2% vs 92.2%), report poor health (32.6% vs. 19.5%), have health insurance (99.1% vs. 93.5%), and have more than two comorbidities (44.4% vs. 32.5%). After adjustment for covariates, breast cancer survivors had 1.7 times (95% CI: 1.15, 2.59) higher odds of adherence to CRC screening than women without a cancer history. However, we observed no significant association between history of breast cancer and adherence to LC screening (aOR: 1.10; 95% CI: 0.68, 1.78). Breast cancer survivors demonstrated higher adherence to CRC screening, but not LC screening. The lung is a common site of breast cancer metastasis; therefore, appropriate LC screenings remain an actionable aspect to improve early cancer detection. Survivorship care in the primary care setting provides the opportunity to emphasize comprehensive preventive screening beyond breast cancer surveillance. Interventions that integrate primary care and oncology follow-up may promote adherence to guideline-recommended screening for early detection and reduce SPCs in breast cancer survivors. Pranali G. Patel, Jennifer Anyanwu, Chaitali Dagli, Mrudula Nair, Minerva So, Eric Adjei Boakye, Adebola O. Adegboyega. Colorectal and lung cancer screening behaviors among breast cancer survivors [abstract]. In: Proceedings of the 19th AACR Conference on the Science of Cancer Health Disparities; 2026 Oct 18-21; Atlanta, GA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2026;35(10 Suppl):Abstract nr B155.