Comparative Evaluation of Different Types of Remineralizing Toothpastes on White Spot Lesions: An In Vitro Study

Abstract

Background: White spot lesions (WSLs) are a frequent complication of fixed orthodontic treatment due to plaque accumulation and enamel demineralization. Aim: To compare the remineralization efficacy of different commercially available toothpastes on WSLs using surface microhardness analysis. Materials and Methods: Sixty extracted human premolars were demineralized and divided into four groups: artificial saliva (control), Sensodyne ProEnamel, Vantej (nano-hydroxyapatite), and Amflor (amine fluoride). Surface microhardness (VHN) was measured at baseline, post-demineralization, and post-remineralization. Statistical analysis included ANOVA and Tukey’s post hoc test. Results: Significant reduction in microhardness occurred after demineralization (p < 0.001). Maximum remineralization was observed with Amflor (94.7%), followed by Vantej (57.6%) and Sensodyne (29.6%). Conclusion: Amine fluoride toothpaste showed superior remineralization potential and can be recommended for prevention of WSLs in orthodontic patients