Jun 2026· Expert Review of Medical Devices· 0 citations· 15 references
Medicine
TL;DR
Prism combined with BVT effectively improves visual function and quality of life in IXT patients, demonstrating safety and clinical value.
Abstract
Background
Given the high prevalence and progressive nature of intermittent exotropia (IXT), effective interventions are urgently needed. We aimed to probe the impact of prism combined with binocular visual training (BVT) on visual function and quality of life in patients with IXT.
RESEARCH
Design
AND
Methods
This was a randomized controlled trial. Eighty-six IXT patients were randomly assigned to the control group (prism only) and experimental group (prism + BVT). Outcomes included strabismus angle, fusion range, stereopsis function, uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), tear film breakup time (TBUT), and refraction, quality of life [Chinese version of intermittent exotropia questionnaires (CIXTQ) scores], and visual discomfort symptoms.
Results
After treatment, compared with the control group, the experimental group showed greater improvements in 33 cm and 6 m strabismus prism diopter, strabismus circular angle, fusion range, distant and near stereopsis detection rates, correct eye alignment, UCVA, BCVA, TBUT, and refraction (p < 0.05). Additionally, the experimental group had higher CIXTQ scores for social psychology and visual function, and a lower incidence of visual discomfort symptoms (p < 0.05).
Conclusion
Prism combined with BVT effectively improves visual function and quality of life in IXT patients, demonstrating safety and clinical value.
CLINICAL TRIAL REGISTRATION
https://www.chictr.org.cn/index.html. Clinical Trial Registration Number: ChiCTR2200112320.
Administering vision therapy in conjunction with patching significantly improved VA, stereo acuity, and accommodation facility in bilateral refractive amblyopia compared to patching alone.
Saeedeh Hoseinmenni, S. Rahmani, Ebrahim Jafarzadehpour et al.· Journal of Ophthalmic & Visi...· 0 citations
AIM
To evaluate changes in visual acuity and accommodation function following femtosecond laser-assisted in situ keratomileusis (FS-LASIK) combined with monovision in patients aged over 40y.
METHODS
This prospective, non-randomized cohort study included patients who were divided into an FS-LASIK binocular group (full correction) and an FS-LASIK monovision group. The binocular group consisted of Group 1 (15 patients) with simple myopia and Group 2 (12 patients) with myopia and presbyopia. The monovision group (Group 3) included 13 patients with myopia and presbyopia. Parameters assessed included the uncorrected distance visual acuity (UCVA), the uncorrected near visual acuity (UNVA), contrast sensitivity (CS), binocular cross-cylinder (BCC), accommodative amplitude (AMP), positive relative accommodation (PRA), negative relative accommodation (NRA), and accommodative facility (AF). Patient satisfaction was evaluated at 3mo postoperatively.
RESULTS
A total of 40 patients (80 eyes) were enrolled (mean age 43.63±3.666y; 12 males). At 3mo after FS-LASIK, UCVA improved significantly in all patients (P<0.001), while UNVA remained comparable to preoperative levels (P>0.05). BCC in Group 3 decreased by 0.30±0.43 compared to preoperative levels, showing a statistically significant difference (P=0.037). The AMP in Group 3 showed an increasing trend with greater improvement in the nondominant eye than in the dominant eye (P>0.05). Patient satisfaction was high in all groups.
CONCLUSION
FS-LASIK combined with monovision is an effective treatment for patients aged over 40y with myopia and presbyopia, which not only improves visual acuity but also achieves high patient satisfaction and improves postoperative BCC.
Yuanyuan Qi, Qi Li, Gui-Li Wang et al.· International Journal of Oph...· 0 citations
Luminopia demonstrated significant improvements in Registry patients with severe amblyopia, particularly in treatment-naive patients, supporting its use as a viable treatment option that may address key limitations of traditional approaches.
Courtney L. Kraus, A. Godfrey, E. Gaier et al.· Journal of AAPOS· 1 citation
AIM
To evaluate the effectiveness of combining patching with active vision therapy, compared to patching with placebo training on contrast sensitivity (CS) in pediatric participants with bilateral refractive amblyopia.
METHODS
In this double-blind, clinical trial, 43 participants aged 5-8 with bilateral refractive amblyopia, unresponsive to spectacles, were randomly assigned to either the experimental group (active vision therapy plus patching) or the control group (placebo treatment with patching) for four months. Active therapy included anti-suppression, accommodative, vergence, and visual memory exercises. CS was measured at baseline and after four months, serving as key outcome measures.
RESULTS
Forty participants (20 in each group) completed the study. The mean age for the experimental group (5 males) was 6.10±0.84y, and 6.50±1.15y for the control group (11 males). CS in the experimental group improved by 0.10 log (right eye), 0.14 log (left eye), and 0.07 log binocularly (P≤0.03). The control group showed no statistically significant enhancements in monocular or binocular CS (P≥0.07). Compared to the control group, the experimental group demonstrated a rate of change in monocular CS of 0.05 during follow-up time.
CONCLUSION
Active vision therapy leads to significant and accelerates improvements in CS among children with bilateral refractive amblyopia.
Saeed Rahmani, Saeedeh Hoseinmenni, C. Dehghani et al.· International Journal of Oph...· 0 citations
This prototype MRG image translocation software was helpful to 69% of patients with binocular diplopia, but limited by large angle strabismus because of the limited instrument field of view.
Edsel B Ing, Kevin Sha, Sarosh Dandoti et al.· Journal of neuro-ophthalmolo...· 0 citations