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DIAGNOSIS AND MANAGEMENT OF SELECTED PRECANCEROUS LESIONS IN ORAL MEDICINE

Sep 2026 · Macedonian Medical Electronic Journal · 0 citations

Abstract

Background

Oral potentially malignant disorders represent a significant concern in oral medicine due to their risk of progression to oral squamous cell carcinoma. Early detection and appropriate management are essential for reducing morbidity and improving patient outcomes.

Objective

The aim of this review is to summarize the clinical features, diagnostic approaches, and current treatment modalities for selected oral precancerous lesions.

Methods

A narrative review was conducted focusing on the most common oral potentially malignant disorders, including oral leukoplakia, erythroplakia, oral lichen planus, oral submucous fibrosis, and actinic cheilitis. Particular emphasis was placed on clinical assessment, identification of risk factors, and histopathological confirmation by biopsy.

Results

Biopsy remains the gold standard for assessing malignant potential. Management depends on the type and severity of the lesion and may include elimination of etiological factors, pharmacological therapy, surgical excision, laser treatment, and long-term surveillance. Malignant transformation may occur even after treatment.

Conclusion

Early diagnosis, timely intervention, and continuous follow-up are essential for reducing the risk of progression to oral cancer.

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