A comprehensive update on the functional and clinical potential of miRNAs as non-invasive biomarkers and therapeutic targets for the management of PCOS and the regulatory role of the gut microbiota-miRNA axis, exosomal miRNAs and the complexity of competitive endogenous RNA networks.
Pilot study results suggest potential miRNAs and their target pathway links with PCOS that need validation in larger cohorts for diagnostic or therapeutic applications need validation in larger cohorts for diagnostic or therapeutic applications.
Recent scientific findings on the role of lncRNAs in the pathophysiology of female infertility are summarized and their potential for the development of novel diagnostic and therapeutic approaches is evaluated.
Tayyebeh Zamani-Badi, Azadeh Sadat Azadbakhsh, Saeedeh Ghazaey Zidanloo et al.· Clinical and Experimental Re...· 0 citations
It is indicated that miR-21 could be a potential biomarker for assessing the disease course and metabolic disorders in PCOS and more large-scale studies are needed to validate its diagnostic and prognostic value.
H. Lateef· Al-Kufa University Journal f...· 0 citations
While ncRNAs represent promising candidates for migraine biomarkers and therapeutic targets, their clinical translation requires rigorous validation beyond current proof-of-concept studies.
Li Zhang, Di-Jun Wang, Wei-Qi Wang et al.· Frontiers in Neurology· 0 citations
The ongoing investigations of the association of genetic polymorphisms with PCOS emphasize the complexity of this disease but also highlight the discrepancies in results with respect to genetic factors involved in the syndrome.
S. Preethi, Gurupavan kumar Ganta, Periasamy Anbu et al.· 0 citations
A focused narrative review examines microRNAs involved in SSc fibrosis, vasculopathy, and immune dysregulation; extracellular-particle-associated microRNAs; and circulating and hair-derived microRNAs as candidate biomarkers; and summarizes evidence on long non-coding RNAs (lncRNAs), circular RNAs, circular RNAs, yRNAs,...
