Open access
CBX4 and NOX4 Expression Are Associated With Chemoradiotherapy Response and Overall Survival in Locally Advanced Cervical Squamous Cell Carcinoma
Xianyu Pang
Xi-Yun Qin
Li-Lin Que
Wei-Ye Li
Zi-Xuan Yang
Wei-Li Yi
Jiao Tang
Yong Zhang
Shan-Shan Ma
Lin-Jiang Pan
Fang Wu
Medicine
Abstract
Tissue biomarkers may improve risk stratification in locally advanced cervical cancer before definitive concurrent chemoradiotherapy (CCRT). We evaluated pretreatment expression of chromobox 4 (CBX4), NADPH oxidase 4 (NOX4), specificity protein 1 (SP1), and copper transporter 1 (CTR1) in relation to CCRT response and overall survival.