Review

Emerging CAR-T Cell Therapies for T Cell Malignancies: Innovations, Challenges, and Future Directions

H. Hetta Fawaz E. Alanazi Mahmoud H. El-Maghrabey S. Bukhari Z. Alatawi Kamel A. Saleh Y. N. Ramadan Ahmed A. Kotb

Aug 2026 · Journal of Pharmaceutical Innovation · Vol 22 · 0 citations · 96 references

TL;DR

Continued efforts to identify highly specific target antigens, optimize manufacturing processes, enhance safety, and integrate CAR-T therapy with complementary immunotherapeutic approaches are expected to improve clinical outcomes and broaden the application of CAR-T therapy to T-cell malignancies and potentially other solid and hematologic cancers.

DOI Semantic Scholar

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