AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
TL;DR
A stratified research framework is proposed to examine how age, inflammatory phenotype, systemic disease, apical anatomy, and regional heterogeneity of the pulp microenvironment may influence regenerative responses.
The objective of this narrative review is to critically evaluate how native dental pulp-derived DPECM is prepared and delivered, what biological effects and candidate mechanisms are directly supported, and what evidence gaps limit clinical translation.
A narrative review examines the dentin-pulp complex from a microengineering perspective, focusing on strategies to engineer vascular, immune, and mineralized niches using bioactive and immune-informed materials to enable predictable and functional regeneration of the dentin-pulp complex.
Findings suggest that dynamic hydrogels do not simply suppress inflammatory signaling but may modulate inflammatory and tissue remodeling pathways while promoting angiogenesis-associated responses.
Existing preclinical evidence indicates that DPSC-EVs exhibit substantial capacity for DPC regeneration, and these outcomes support continued translational research of DPSC-EVs as a promising cell-free regenerative approach; nonetheless, clinical implementation awaits validation via large-animal and human clinical stud...
Oral diseases impact approximately 3.5 billion individuals globally, often leading to the loss or damage of periodontal, alveolar bone, dentin-pulp, or oral soft tissues. Consequently, dental tissue engineering necessitates scaffolds that can simultaneously offer a three-dimensional extracellular matrix-like microenvir...
Current evidence on the origin, phenotype, and function of macrophages in the dental pulp is summarized, with particular emphasis on their interaction with DPSCs under inflammatory conditions.
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