Jul 2026· Journal of Biomimetics, Biomaterials and Biomedical Engineering· Vol 73, pp. 79 - 95· 0 citations· 27 references
Abstract
This study examines the physicochemical properties of a hydrogel composed of poly(vinyl alcohol) (PVA) and bacterial cellulose (BC), modified with silver nanoparticles (AgNPs) previously synthesised via green methods using Lactobacillus acidophilus UCM B-2691. The effects of composition on moisture content, sorption behavior, and moisture desorption were assessed, and the density of the obtained samples was investigated. Increasing the bacterial cellulose content in hydrogels enhances their hydrophilicity, water-holding capacity, and sorption properties. The incorporated AgNPs are not released from the hydrogels and do not exhibit antimicrobial activity; instead, they promote the formation of a more porous, structurally stable network, which enhances sorption and lowers density. PVA/BC hydrogels containing 40–60% BC and AgNPs showed the best overall performance, combining high hydrophilicity, structural stability, and porosity. The results indicate the high potential of these hydrogel systems for biomedical technologies, particularly in controlled drug delivery and tissue engineering.
Compared to PVA hydrogels, the composite hydrogels minimized the initial burst release and prolonged the stability of BSA over extended periods, thereby highlighting their potential applications in wound healing and tissue engineering.
Yan-Qi Li, Jin-Heng Liu, Guangxin Wang et al.· Polymer Engineering & Sc...· 0 citations
Overall, ZnONPs improved antibacterial activity, HAp provided the most favorable cytocompatibility and stability profile, while GONs showed a comparatively higher hemolytic response, highlighting the importance of nanoparticle selection in designing PVA/SA hydrogel scaffolds for tissue-contact applications.
N. Abuhamed, E. Dinçer, K. Öksüz· ACS Omega· 0 citations
Overall, the developed Gelatin-g-PAAc/MWCNT-COOH nanocomposite hydrogels exhibit favorable structural, swelling, biocompatible, and electro-responsive characteristics, making them promising candidates for the design of advanced electrically controlled drug delivery systems.
P. Gogoi, Monalisha Boruah· International Journal of Lat...· 0 citations
The results show that FT treatment effectively stabilizes PVA nanofibers and significantly slows down the release of incorporated PL, and offers a promising platform for developing safe, functional nanofibrous materials for chronic wound treatment and skin regeneration.
Maxim Lisnenko, S. Hauzerova, Kateřina Strnadová et al.· ACS Omega· 0 citations
The objective of this study is the preparation of new copolymer hydrogels with featured properties such as non-toxic, biocompatible, and biodegradable characteristics that can be used in different biomedical applications. Therefore, the superabsorbent hydrogels were prepared mostly from natural polymers that grafted wi...
