Skip to content
Open access

Effect of Propofol versus Sevoflurane on Postoperative Shivering during Maintenance of General

Jul 2026 · International Journal of Pharmaceutical Quality Assurance · Vol 16 · 0 citations · 19 references

TL;DR

Propofol provided superior hemodynamic control, faster recovery, and fewer postoperative adverse effects compared to sevoflurane, making it a preferable agent for maintenance of anesthesia in short elective surgeries.

Abstract

Background: The choice of anesthetic agent for maintenance of general anesthesia significantly influences intraoperative stability, ‘ recovery profile, and postoperative outcomes. Propofol and sevoflurane are commonly used agents, yet their comparative performance remains clinically relevant. Aim: To compare propofol and sevoflurane for maintenance of anesthesia with respect to hemodynamic stability, recovery characteristics, and adverse events. Methodology: This prospective, randomized comparative study included 80 ASA I–II patients undergoing elective surgeries. Patients were allocated into two groups: Group P (propofol infusion) and Group S (sevoflurane inhalation). Hemodynamic parameters, recovery times, Modified Aldrete Score, and perioperative adverse events were assessed and analyzed statistically. Results: Demographic variables were comparable between groups. Group P demonstrated significantly better intraoperative hemodynamic stability with lower heart rate and blood pressure values (p < 0.05). Recovery was faster in Group P, with shorter times to eye opening, verbal response, and extubation (p < 0.001). Postoperative nausea, vomiting, and emergence agitation were significantly lower with propofol. Conclusion: Propofol provided superior hemodynamic control, faster recovery, and fewer postoperative adverse effects compared to sevoflurane, making it a preferable agent for maintenance of anesthesia in short elective surgeries.

Read PDF

Similar papers

Open access Oct 2026

Ciprofol versus propofol for general anesthesia during thoracoscopic surgery: a randomized double-blind trial

Ciprofol is a novel intravenous anesthetic with potentially improved hemodynamic stability and fewer injection-related adverse effects than propofol. This study compared ciprofol and propofol for general anesthesia in patients undergoing video-assisted thoracoscopic surgery (VATS). In this prospective, ran...

Yu Wang, Yi-Zhi Geng, Yao-Dong Yan et al. · 0 citations
Open access Aug 2026

Prospective observational comparison of propofol–ketamine, propofol–fentanyl, propofol– dexmedetomidine combinations on intraoperative hemodynamics, post-operative recovery in upper abdominal surgery

Balanced general anesthesia optimization remains challenging as propofol adjuvants (dexmedetomidine, fentanyl, ketamine) uniquely affect intraoperative hemodynamics and post-operative recovery profiles. Therefore, it is of interest to compare the propofol-dexmedetomidine (PD), propofol-fentanyl (PF) and propofol-ketami...

Sonali Tripathia · 0 citations
Open access Sep 2026

UTILIZATION AND ADVERSE EFFECT PROFILE OF PROPOFOL, MIDAZOLAM, FENTANYL, AND ONDANSETRON IN THE PERIOPERATIVE PERIOD: A PROSPECTIVE OBSERVATIONAL STUDY

Objectives: The objective of this study was to assess the perioperative utilization pattern of propofol, midazolam, fentanyl, and ondansetron and to describe the frequency and profile of associated adverse events among adult surgical patients. Methods: This prospective observational study included 100 adult patients un...

Meela Ranjith Kumar, Lee Mb, Manchala Priyanka et al. · 0 citations
Open access Sep 2026

Effect of Intraoperative Administration of Dexamethasone on Postoperative Shivering in Patients Undergoing General Anesthesia

Objectives: 1. This study aims to understand whether dexamethasone is an effective drug for the prevention of postoperative shivering in patients undergoing general anesthesia. 2. The research will aid in minimizing the occurrence of shivering by providing appropriate treatment. Settings: The study was carried out in t...

Nimrah Farook, Nasir Ali Rahim Najjad, Mansoor Chandio et al. · 0 citations
Open access Sep 2026

Desflurane and target-controlled propofol for craniotomy: A randomized trial

Selecting the optimal anaesthetic technique for craniotomy remains challenging because desflurane and target-controlled infusion (TCI) propofol differ in cerebral and recovery effects. Sixty ASA I-III patients undergoing elective supratentorial craniotomy were randomized to desflurane or TCI propofol and brain relaxati...

Bhavana Pinnaka · 0 citations
Open access Jan 2026

Effect of Low‐Dose Propofol Administered at the End of Sevoflurane Anesthesia on Emergence Agitation in Pediatric Patients Undergoing MRI: A Randomized Controlled Trial

Background Emergence agitation (EA) is a common postanesthetic problem in pediatric patients, particularly with sevoflurane anesthesia, and may lead to injury to patients, prolonged postanesthesia care unit (PACU) stay, and a risk of long‐term maladaptive behavioral changes. Evidence regarding EA in nonpainful procedur...

Thitinuch Ruenhunsa, Santhita Pimonbut, Peerapong Sangsungnern et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.