Jul 2026· International Journal of Pharmaceutical Quality Assurance· Vol 16· 0 citations· 19 references
TL;DR
Propofol provided superior hemodynamic control, faster recovery, and fewer postoperative adverse effects compared to sevoflurane, making it a preferable agent for maintenance of anesthesia in short elective surgeries.
Abstract
Background: The choice of anesthetic agent for maintenance of general anesthesia significantly influences
intraoperative stability, ‘
recovery profile, and postoperative outcomes. Propofol and sevoflurane are commonly
used agents, yet their comparative performance remains clinically relevant.
Aim: To compare propofol and sevoflurane for maintenance of anesthesia with respect to hemodynamic stability,
recovery characteristics, and adverse events.
Methodology: This prospective, randomized comparative study included 80 ASA I–II patients undergoing
elective surgeries. Patients were allocated into two groups: Group P (propofol infusion) and Group S (sevoflurane
inhalation). Hemodynamic parameters, recovery times, Modified Aldrete Score, and perioperative adverse events
were assessed and analyzed statistically.
Results: Demographic variables were comparable between groups. Group P demonstrated significantly better
intraoperative hemodynamic stability with lower heart rate and blood pressure values (p < 0.05). Recovery was
faster in Group P, with shorter times to eye opening, verbal response, and extubation (p < 0.001). Postoperative
nausea, vomiting, and emergence agitation were significantly lower with propofol.
Conclusion: Propofol provided superior hemodynamic control, faster recovery, and fewer postoperative adverse
effects compared to sevoflurane, making it a preferable agent for maintenance of anesthesia in short elective
surgeries.
Ciprofol is a novel intravenous anesthetic with potentially improved hemodynamic stability and fewer injection-related adverse effects than propofol. This study compared ciprofol and propofol for general anesthesia in patients undergoing video-assisted thoracoscopic surgery (VATS).
In this prospective, ran...
Yu Wang, Yi-Zhi Geng, Yao-Dong Yan et al.· Frontiers in Medicine· 0 citations
Balanced general anesthesia optimization remains challenging as propofol adjuvants (dexmedetomidine, fentanyl, ketamine) uniquely affect intraoperative hemodynamics and post-operative recovery profiles. Therefore, it is of interest to compare the propofol-dexmedetomidine (PD), propofol-fentanyl (PF) and propofol-ketami...
Objectives: The objective of this study was to assess the perioperative utilization pattern of propofol, midazolam, fentanyl, and ondansetron and to describe the frequency and profile of associated adverse events among adult surgical patients.
Methods: This prospective observational study included 100 adult patients un...
Meela Ranjith Kumar, Lee Mb, Manchala Priyanka et al.· Asian Journal of Pharmaceuti...· 0 citations
Objectives: 1. This study aims to understand whether dexamethasone is an effective drug for the prevention of postoperative shivering in patients undergoing general anesthesia. 2. The research will aid in minimizing the occurrence of shivering by providing appropriate treatment. Settings: The study was carried out in t...
Nimrah Farook, Nasir Ali Rahim Najjad, Mansoor Chandio et al.· SAR Journal of Medicine· 0 citations
Selecting the optimal anaesthetic technique for craniotomy remains challenging because desflurane and target-controlled infusion (TCI) propofol differ in cerebral and recovery effects. Sixty ASA I-III patients undergoing elective supratentorial craniotomy were randomized to desflurane or TCI propofol and brain relaxati...
Background Emergence agitation (EA) is a common postanesthetic problem in pediatric patients, particularly with sevoflurane anesthesia, and may lead to injury to patients, prolonged postanesthesia care unit (PACU) stay, and a risk of long‐term maladaptive behavioral changes. Evidence regarding EA in nonpainful procedur...
Thitinuch Ruenhunsa, Santhita Pimonbut, Peerapong Sangsungnern et al.· Anesthesiology Research and...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.