Jul 2026· Expert Review of Gastroenterology & Hepatology· pp. 1-17· 0 citations· 112 references
Medicine
TL;DR
This expert opinion review synthesizes evidence identified via a narrative search of MEDLINE/PubMed and key guideline/reference screening, focusing on GI dysfunction as a barrier to enteral nutrition in the ICU, phase-adapted energy and protein provision, and strategies to restore intake during ward recovery and after discharge.
Abstract
INTRODUCTION
Survivorship after critical illness is frequently complicated by muscle wasting and gastrointestinal (GI) dysfunction, driving prolonged functional impairment. Nutrition is a modifiable determinant across the intensive care unit (ICU)-to-home continuum, yet delivery is commonly limited by feeding intolerance and fragmented transitions of care.
AREAS COVERED
This expert opinion review synthesizes evidence identified via a narrative search of MEDLINE/PubMed and key guideline/reference screening, focusing on GI dysfunction as a barrier to enteral nutrition (EN) in the ICU, phase-adapted energy and protein provision, and strategies to restore intake during ward recovery and after discharge, including high-energy, protein-dense oral nutritional supplements (ONS).
EXPERT OPINION
Nutrition should be delivered as a structured pathway rather than a single ICU intervention. Early EN with proactive, symptom-targeted management of GI dysfunction, coupled with stepwise protein escalation aligned to metabolic phase and organ function, may help reduce avoidable deficits. The early post-ICU period is an anabolic 'window of opportunity' that warrants intake monitoring, deliberate tapering of tube feeds only once oral intake is reliable, and routine post-discharge ONS for patients at nutritional risk. Research should prioritize pragmatic trials of phase-specific targets and transition-of-care models.
Background: Nutritional support in critically ill patients remains one of the most debated aspects of intensive care medicine. Although international guidelines have long recommended early nutritional support with progressive protein delivery, recent clinical evidence has questioned the benefit of aggressive early calo...
M. Stoian, A. Stoian, C. Bănescu et al.· Nutrients· 0 citations
PURPOSE
Improved survival from critical illness has produced a growing population of intensive care unit (ICU) survivors with new or worsened physical, cognitive, and mental-health impairment, defined as post-intensive care syndrome (PICS), and frequent distress among families/caregivers (PICS-family, PICS-F). This nar...
Stefan J. Schaller, T. Cardoso, Sabrina Eggmann et al.· Intensive Care Medicine· 0 citations
Patients with nasopharyngeal carcinoma (NPC) undergoing definitive treatment commonly experience muscle loss, nutritional deterioration, symptom burden, and functional decline, increasing sarcopenia risk. This study aimed to develop a context-sensitive supportive care pathway integrating multidisciplinary care strategi...
Li-Juan Xia, Su-Juan Chen, J. Min et al.· Supportive Care in Cancer· 0 citations
Children with cancer who require pediatric intensive care encounter overlapping metabolic insults from cancer biology, anticancer treatment, and critical illness. These insults may produce a dynamic malnutrition phenotype characterized by impaired intake or absorption, rapid lean-mass loss, micronutrient and electrolyt...
Pei-Yu Huang, Zhiyi Deng· Cancer Plus· 0 citations
BackgroundMalnutrition affects nearly half of patients in Canadian hospitals and is associated with increased complications, longer hospital stays, and higher mortality. Audits at an urban acute care hospital identified gaps in nutrition screening, oral intake monitoring, weight surveillance, and interdisciplinary coor...
Indershini Pillay, Tanya M T Choy, J. C. Leung et al.· Nutrition and Health· 0 citations
Malnutrition is a common and potentially modifiable risk factor among patients undergoing gastrointestinal oncology surgery and is associated with increased postoperative complications, prolonged hospital stay, delayed functional recovery, impaired tolerance of adjuvant therapy, and hospital readmissions. Enhanced reco...
N. Thakur, Sahil Goel, Himanshu Agrawal et al.· World Journal of Clinical Ca...· 0 citations
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